使用EnrichmentMap在网页上进行基因集富集分析和可视化：RNA测序。

Gene-set enrichment analysis and visualization on the web using EnrichmentMap:RNASeq.

作者信息

Franz Max, Lopes Christian T, Kucera Mike, Voisin Veronique, Isserlin Ruth, Bader Gary D

机构信息

The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada.

Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada.

出版信息

Bioinform Adv. 2025 Jul 24;5(1):vbaf178. doi: 10.1093/bioadv/vbaf178. eCollection 2025.

DOI:10.1093/bioadv/vbaf178

PMID:40861393

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12373637/

Abstract

SUMMARY

EnrichmentMap: RNASeq (enrichmentmap.org) is an intuitive, web-based app for gene-set enrichment analysis and visualization, specifically supporting two-case RNA-Seq experiments for Homo sapiens. The web app introduces a simplified user interface, faster processing times, and eliminates the need for software installation compared to running similar workflows in the Cytoscape desktop software, catering to biologists with minimal computational experience. EnrichmentMap: RNASeq is a new type of Cytoscape web app that is interoperable with Cytoscape.

AVAILABILITY AND IMPLEMENTATION

The app is available to use at enrichmentmap.org and the source code is available at github.com/cytoscape/enrichment-map-webapp.

摘要

富集图：RNA测序（enrichmentmap.org）是一款直观的基于网络的应用程序，用于基因集富集分析和可视化，特别支持针对智人的双样本RNA测序实验。与在Cytoscape桌面软件中运行类似工作流程相比，该网络应用程序引入了简化的用户界面，处理时间更快，并且无需安装软件，适合计算经验最少的生物学家使用。富集图：RNA测序是一种新型的与Cytoscape可互操作的网络应用程序。