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因疟疾行急诊剖宫产:围手术期挑战

Emergent Cesarean Section Due to Malaria: A Perioperative Challenge.

作者信息

Bandarupalli Tanmai, Zbeidy Reine

机构信息

Medicine, University of Central Florida College of Medicine, Orlando, USA.

Anesthesiology and Perioperative Medicine, University of Miami, Miami, USA.

出版信息

Cureus. 2025 Jul 23;17(7):e88621. doi: 10.7759/cureus.88621. eCollection 2025 Jul.

DOI:10.7759/cureus.88621
PMID:40861575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12373431/
Abstract

In a nonendemic setting, the confluence of malaria and pregnancy presents unique anesthetic challenges, particularly when the infection is undiagnosed at the time of an urgent cesarean section. This report involves a woman in her early 30s at 39 weeks of gestation with no prior health issues, who developed malarial symptoms upon returning from Haiti five months before. During labor, severe fetal heart rate decelerations necessitated immediate surgical intervention. Given the patient's febrile state, rapid induction with etomidate and succinylcholine was selected to minimize hemodynamic instability and secure the airway swiftly. Intraoperatively, close monitoring guided the systemic effects of malaria, such as hypotension and coagulation anomalies. Following delivery, empirical antimalarial treatment was initiated before the confirmatory diagnosis, considering the etiology endemic to the patient's travel history. This case emphasizes the role of flexible, anticipatory anesthetic strategies in urgent obstetric procedures, specifically those involving complex infectious conditions.

摘要

在非疟疾流行地区,疟疾与妊娠并存带来了独特的麻醉挑战,尤其是在紧急剖宫产时感染未被诊断出来的情况下。本报告涉及一名30岁出头、妊娠39周的女性,她之前没有健康问题,在五个月前从海地返回后出现了疟疾症状。分娩期间,严重的胎儿心率减速需要立即进行手术干预。鉴于患者的发热状态,选择依托咪酯和琥珀酰胆碱进行快速诱导,以尽量减少血流动力学不稳定并迅速确保气道安全。术中,密切监测指导了疟疾的全身影响,如低血压和凝血异常。分娩后,在确诊之前就开始了经验性抗疟治疗,考虑到患者旅行史中的地方病病因。本病例强调了灵活、前瞻性麻醉策略在紧急产科手术中的作用,特别是那些涉及复杂感染情况的手术。

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本文引用的文献

1
Anesthetic management of urgent cesarean delivery in a parturient with acute malaria infection: a case report.急性疟疾感染产妇紧急剖宫产的麻醉管理:一例报告
Korean J Anesthesiol. 2016 Apr;69(2):193-6. doi: 10.4097/kjae.2016.69.2.193. Epub 2016 Mar 30.
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The clinical implications of thrombocytopenia in adults with severe falciparum malaria: a retrospective analysis.成人重症恶性疟血小板减少症的临床意义:一项回顾性分析。
BMC Med. 2015 Apr 24;13:97. doi: 10.1186/s12916-015-0324-5.
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Immunol Res. 2012 Dec;54(1-3):254-61. doi: 10.1007/s12026-012-8303-9.
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Anaesthetic management of caesarean delivery in a parturient with malaria.产妇疟疾行剖宫产术的麻醉管理。
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