Menotti A, Seccareccia F
J Epidemiol Community Health. 1985 Dec;39(4):325-9. doi: 10.1136/jech.39.4.325.
Altogether 99 029 men aged 40-59, employed on the Italian railroad system, were classified in three levels of physical activity at work and three levels of job responsibility and then followed up for five years in terms of mortality and cause of death. Physical activity and job responsibility have been investigated in different ways as possible risk factors of lethal events. When considering together the findings of univariate and bivariate analyses it appears that low physical activity and high job responsibility are attributes favouring myocardial infarction, and that high physical activity and low job responsibility are attributes favouring lethal chronic bronchitis and violent death. Overall, mortality from all causes is not significantly different in different classes of physical activity and job responsibility, and within total mortality these two characteristics play a role in the distribution of the various causes of death as a consequence of possible competing risks. A number of other non-measured factors, however, may have had a confounding effect.
共有99029名年龄在40至59岁之间、受雇于意大利铁路系统的男性，根据工作中的身体活动水平和工作职责水平分为三个等级，然后对其进行了为期五年的死亡率和死因随访。身体活动和工作职责已作为致死事件的可能风险因素，通过不同方式进行了调查。综合单变量和双变量分析的结果来看，身体活动水平低且工作职责高似乎是有利于心肌梗死的属性，而身体活动水平高且工作职责低则是有利于致死性慢性支气管炎和暴力死亡的属性。总体而言，不同身体活动和工作职责类别中的全因死亡率并无显著差异，在总死亡率范围内，由于可能存在的竞争风险，这两个特征在各种死因的分布中发挥了作用。然而，一些其他未测量的因素可能产生了混杂效应。
