Menotti A, Puddu V
Scand J Work Environ Health. 1979 Jun;5(2):100-8. doi: 10.5271/sjweh.2663.
A cohort of 172,489 males aged 20--64 years and employed by the Italian railroad system on 1 April 1963 have been classified by habitual physical activity at work and followed-up for death during a ten-year period. The overall crude mortality was 56.59 per 1,000 in ten years, and no significant differences were found between men in sedentary, moderate and heavy work. Age-corrected death rates for coronary heart disease, as manifested by myocardial infarction and sudden coronary death, were substantially different in the three activity groups, moderately active workers ranking first, sedentary workers second, but very close to the former, and very active workers being last. The age-corrected rates for all ages were 14.18, 12.55 and 7.63 per 1,000 in ten years, respectively. All differences were statistically significant, the mortality ratio between the sedentary and moderate groups combined versus the heavy group being of the order of 1.75 to 1.
1963年4月1日受雇于意大利铁路系统的172489名年龄在20至64岁之间的男性，已根据工作中的习惯性体力活动进行分类，并在十年期间对其死亡情况进行了随访。十年间总的粗死亡率为每1000人中有56.59人，久坐工作、中度工作和重度工作的男性之间未发现显著差异。以心肌梗死和冠心病猝死表现的冠心病年龄校正死亡率在三个活动组中存在显著差异，中度体力活动的工人排名第一，久坐工作的工人排名第二，但与前者非常接近，而体力活动非常频繁的工人排名最后。所有年龄段的年龄校正率在十年间分别为每1000人中有14.18人、12.55人和7.63人。所有差异均具有统计学意义，久坐和中度活动组合并与重度活动组之间的死亡率比约为1.75比1。
