Sanders E A, Ongerboer de Visser B W, Barendswaard E C, Arts R J
J Neurol Neurosurg Psychiatry. 1985 Dec;48(12):1284-9. doi: 10.1136/jnnp.48.12.1284.
Jaw, blink and corneal reflexes, which all involve the trigeminal system, were recorded in 54 patients with multiple sclerosis; thirty-seven of these patients were classified as having definite multiple sclerosis and 17 as indefinite multiple sclerosis, according to Schumacher's criteria. The jaw reflex was abnormal less frequently than either of the other two reflexes, but in four cases it was the only abnormal reflex found. Testing a combination of two or three trigeminal reflexes did not yield a higher incidence of abnormalities than testing the blink or corneal reflex alone. Nine patients showed abnormal reflexes which were unexpected on the basis of clinical symptoms. The combined recordings demonstrate at least one abnormal reflex in 74% of the patients. The various types of reflex abnormalities reflect major damage to different parts of the trigeminal system and may therefore make an important contribution to the diagnosis of multiple sclerosis.
对54例多发性硬化患者记录了涉及三叉神经系统的下颌、瞬目和角膜反射；根据舒马赫标准，其中37例患者被分类为确诊多发性硬化，17例为疑似多发性硬化。下颌反射异常的频率低于其他两种反射中的任何一种，但有4例患者仅发现下颌反射异常。测试两到三种三叉神经反射组合时，异常发生率并不比单独测试瞬目或角膜反射更高。9例患者出现了基于临床症状无法预料的异常反射。综合记录显示，74%的患者至少有一项异常反射。各种类型的反射异常反映了三叉神经系统不同部位的严重损害，因此可能对多发性硬化的诊断有重要帮助。
