Hafez M, Nagaty M, Al-Tonbary Y, el-Shennawy F A, el-Mongui A, el-Sallab S, Attia S
J Neurogenet. 1985 Sep;2(4):285-90. doi: 10.3109/01677068509102324.
A microlymphocytotoxicity test determined serologically the frequency of HLA antigens in 32 patients with Guillain-Barré syndrome and in 234 healthy control subjects. The results demonstrated significantly increased frequencies of A3 and B8. The relative risk was estimated to be 9.6 and 4.6 for the A3 and B8 antigens, respectively. Study of the gametic association revealed weak positive linkage disequilibrium and biological association. The results are discussed, and it is concluded that the aberrant genetic make-up of the patients makes them more susceptible to develop the syndrome after exposure to the environmental factor(s).
一项微量淋巴细胞毒性试验通过血清学方法测定了32例格林-巴利综合征患者和234名健康对照者中HLA抗原的频率。结果显示，A3和B8抗原的频率显著增加。A3和B8抗原的相对风险估计分别为9.6和4.6。对配子关联的研究揭示了弱的正连锁不平衡和生物学关联。对结果进行了讨论，并得出结论，患者异常的基因构成使他们在接触环境因素后更易患该综合征。
