Winer J B, Briggs D, Welsh K, Hughes R A
Department of Neurology United Medical School Guy's Hospital, London, U.K.
J Neuroimmunol. 1988 Apr;18(1):13-6. doi: 10.1016/0165-5728(88)90130-0.
HLA typing for class I and II antigens was performed on 89 caucasoid patients with Guillain-Barré syndrome and compared with controls. No significant association, between HLA type and susceptibility to disease, prognosis at 12 months or antecedent event was discovered. HLA antigen DR2 was more frequent among patients with the most profound muscle weakness.
对89例患有吉兰-巴雷综合征的高加索患者进行了I类和II类抗原的HLA分型,并与对照组进行了比较。未发现HLA类型与疾病易感性、12个月时的预后或前驱事件之间存在显著关联。在肌肉无力最严重的患者中,HLA抗原DR2更为常见。