Gusev Oleg
Intractable Disease Research Center, Graduate School of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Diagnostics (Basel). 2025 Aug 12;15(16):2020. doi: 10.3390/diagnostics15162020.
From the corona virus pandemic in Japan that started with the "Diamond Princess" accident, it became clear that rapid detection, a high sensitivity, multiple diagnostic items, one-step one-base point mutation detection, a fast speed of system development, portability (small size and light weight), full automation, random access, and other conditions are required for future point-of-care testing systems. The Eprimer-SmartAmp technology that was developed possesses characteristics fully aligned with these requirements. Building upon this platform, the "GenPad" system was subsequently established. The GenPad system is widely applicable not only to emerging foreign infectious diseases, but also to cancer, lifestyle-related diseases, and other areas of healthcare through telemedicine and intraoperative nucleic acid diagnoses. In collaboration with telecommunication systems, GenPad is expected to contribute to the establishment of a smart medical city with a countermeasure against emerging foreign infectious diseases, where individuals can check their own health conditions in all healthcare areas.
从以“钻石公主号”事故为开端的日本新冠病毒疫情可以看出，未来的即时检测系统需要具备快速检测、高灵敏度、多项诊断项目、一步法单碱基突变检测、系统开发速度快、便携性（体积小、重量轻）、全自动化、随机存取等条件。所开发的Eprimer-SmartAmp技术具备与这些要求完全相符的特性。在此平台基础上，随后建立了“GenPad”系统。GenPad系统不仅广泛适用于新型外来传染病，还可通过远程医疗和术中核酸诊断应用于癌症、生活习惯病等医疗保健领域。通过与电信系统合作，GenPad有望为建立一个针对新型外来传染病的智能医疗城市做出贡献，在这个城市中，个人可以在所有医疗保健领域检查自己的健康状况。
