• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

MADS盒基因XAANTAL1通过直接调控过氧化物酶28和视网膜母细胞瘤相关基因，参与拟南芥主根生长和柱干细胞模式以响应活性氧。

The MADS-box gene XAANTAL1 participates in Arabidopsis thaliana primary root growth and columella stem cell patterns in response to ROS, via direct regulation of PEROXIDASE 28 and RETINOBLASTOMA-RELATED genes.

作者信息

Zluhan-Martínez Estephania, Castañón-Suárez Claudio A, Gutiérrez-Rodríguez Mario A, Lledías Fernando, Zhang Tao, Peng Jesús T, Dickinson Jazz, Sánchez Rodríguez Diana Belén, Sánchez María de la Paz, García-Ponce Berenice, Álvarez-Buylla Elena R, Garay-Arroyo Adriana

机构信息

Laboratorio de Genética Molecular, Desarrollo y Evolución de Plantas, Departamento de Ecología Funcional, Instituto de Ecología, Universidad Nacional Autónoma de México, Ciudad de México, CP 04510, México.

Posgrado en Ciencias Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México, CP 04510, México.

出版信息

J Exp Bot. 2025 Jan 10;76(2):411-432. doi: 10.1093/jxb/erae415.

DOI:10.1093/jxb/erae415
PMID:39377268
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11714753/
Abstract

The balance between cell growth, proliferation, and differentiation emerges from gene regulatory networks coupled to various signal transduction pathways, including reactive oxygen species (ROS) and transcription factors (TFs), enabling developmental responses to environmental cues. The primary root of Arabidopsis thaliana has become a valuable system for unravelling such networks. Recently, the role of TFs that mediate ROS inhibition of primary root growth has begun to be characterized. This study demonstrates that the MADS-box TF gene XAANTAL1 (XAL1) is an essential regulator of hydrogen peroxide (H2O2) in primary root growth and root stem cell niche identity. Interestingly, our findings indicated that XAL1 acts as a positive regulator of H2O2 concentration in the root meristem by directly regulating genes involved in oxidative stress response, such as PEROXIDASE 28 (PER28). Moreover, we found that XAL1 is necessary for the H2O2-induced inhibition of primary root growth through the negative regulation of peroxidase and catalase activities. Furthermore, XAL1, in conjunction with RETINOBLASTOMA-RELATED (RBR), is essential for positively regulating the differentiation of columella stem cells and for participating in primary root growth inhibition in response to oxidative stress induced by H2O2 treatment.

摘要

细胞生长、增殖和分化之间的平衡源于与各种信号转导途径（包括活性氧（ROS）和转录因子（TFs））耦合的基因调控网络，从而实现对环境线索的发育响应。拟南芥的主根已成为揭示此类网络的重要系统。最近，介导ROS对主根生长抑制作用的TFs的作用已开始得到表征。本研究表明，MADS盒TF基因XAANTAL1（XAL1）是过氧化氢（H2O2）在主根生长和根干细胞龛身份中的关键调节因子。有趣的是，我们的研究结果表明，XAL1通过直接调节参与氧化应激反应的基因（如过氧化物酶28（PER28）），作为根分生组织中H2O2浓度的正调节因子。此外，我们发现XAL1通过对过氧化物酶和过氧化氢酶活性的负调节，对于H2O2诱导的主根生长抑制是必需的。此外，XAL1与视网膜母细胞瘤相关蛋白（RBR）一起，对于正向调节柱干细胞的分化以及参与响应H2O2处理诱导的氧化应激的主根生长抑制至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/fd8cec21c799/erae415_fig10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/d71aa87a4650/erae415_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/b3a126ec92fa/erae415_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/4c9026a6fe75/erae415_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/c403c9f0ec1b/erae415_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/8fbd7a11a6b3/erae415_fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/b8c76f76e5bc/erae415_fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/a0431265bd25/erae415_fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/726f718436ee/erae415_fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/89e4fb64aa0d/erae415_fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/fd8cec21c799/erae415_fig10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/d71aa87a4650/erae415_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/b3a126ec92fa/erae415_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/4c9026a6fe75/erae415_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/c403c9f0ec1b/erae415_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/8fbd7a11a6b3/erae415_fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/b8c76f76e5bc/erae415_fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/a0431265bd25/erae415_fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/726f718436ee/erae415_fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/89e4fb64aa0d/erae415_fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11714753/fd8cec21c799/erae415_fig10.jpg

相似文献

1
The MADS-box gene XAANTAL1 participates in Arabidopsis thaliana primary root growth and columella stem cell patterns in response to ROS, via direct regulation of PEROXIDASE 28 and RETINOBLASTOMA-RELATED genes.MADS盒基因XAANTAL1通过直接调控过氧化物酶28和视网膜母细胞瘤相关基因，参与拟南芥主根生长和柱干细胞模式以响应活性氧。
J Exp Bot. 2025 Jan 10;76(2):411-432. doi: 10.1093/jxb/erae415.
2
Extracellular ATP Receptors P2Ks Play a Role in Regulating Local and Systemic ROS Accumulation of Arabidopsis thaliana Seedlings in Response to Local Salt Stress.细胞外ATP受体P2Ks在调节拟南芥幼苗响应局部盐胁迫时的局部和系统性活性氧积累中发挥作用。
Physiol Plant. 2025 Jul-Aug;177(4):e70381. doi: 10.1111/ppl.70381.
3
RGIs-mediated root apical meristem development is essential for root hydrotropic response in Arabidopsis thaliana.在拟南芥中，由RGIs介导的根尖分生组织发育对于根的向水性反应至关重要。
Plant J. 2025 Jun;122(6):e70273. doi: 10.1111/tpj.70273.
4
An AGAMOUS-related MADS-box gene, XAL1 (AGL12), regulates root meristem cell proliferation and flowering transition in Arabidopsis.一个与AGAMOUS相关的MADS盒基因XAL1（AGL12），调控拟南芥根分生组织细胞增殖和开花转变。
Plant Physiol. 2008 Mar;146(3):1182-92. doi: 10.1104/pp.107.108647. Epub 2008 Jan 18.
5
Impact of Iron Deficiency on the Arabidopsis thaliana Phloem Sap Proteome, a Key Role for bHLH121.缺铁对拟南芥韧皮部汁液蛋白质组的影响，bHLH121的关键作用
Physiol Plant. 2025 May-Jun;177(3):e70336. doi: 10.1111/ppl.70336.
6
Ectopic Expression of MADS-Box Transcription Factor from Grape Promotes Early Flowering, Plant Growth, and Production by Regulating Cell-Wall Architecture in .葡萄 MADS-Box 转录因子的异位表达通过调节细胞壁结构促进 的早期开花、植物生长和产量。
Genes (Basel). 2023 Nov 15;14(11):2078. doi: 10.3390/genes14112078.
7
Exploring the regulatory roles of AtGLR3.4 receptors in mitochondrial stress and ROS management in Arabidopsis.探索拟南芥中AtGLR3.4受体在线粒体应激和活性氧管理中的调控作用。
Plant Cell Rep. 2025 Jul 1;44(7):164. doi: 10.1007/s00299-025-03558-y.
8
The MADS-box XAANTAL1 increases proliferation at the Arabidopsis root stem-cell niche and participates in transition to differentiation by regulating cell-cycle components.MADS盒蛋白XAANTAL1可增加拟南芥根干细胞龛处的细胞增殖，并通过调控细胞周期组分参与细胞分化转变过程。
Ann Bot. 2016 Oct 1;118(4):787-796. doi: 10.1093/aob/mcw126.
9
ANAC044 orchestrates mitochondrial stress signaling to trigger iron-induced stem cell death in root meristems.ANAC044 协调线粒体应激信号传导，以触发根分生组织中铁诱导的干细胞死亡。
Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2411579122. doi: 10.1073/pnas.2411579122. Epub 2024 Dec 30.
10
A CLE14 Signalling Cascade Promotes Arabidopsis Root Hair Elongation.一条CLE14信号级联促进拟南芥根毛伸长。
Plant Cell Environ. 2025 Aug;48(8):6251-6268. doi: 10.1111/pce.15584. Epub 2025 May 7.

引用本文的文献

1
ROS, an Important Plant Growth Regulator in Root Growth and Development: Functional Genes and Mechanism.ROS，一种在根系生长发育中起重要作用的植物生长调节剂：功能基因与机制
Biology (Basel). 2024 Dec 10;13(12):1033. doi: 10.3390/biology13121033.

本文引用的文献

1
The MADS-box genes and antagonize functions in root development.MADS盒基因在根发育中具有拮抗功能。
Front Plant Sci. 2024 Mar 21;15:1331269. doi: 10.3389/fpls.2024.1331269. eCollection 2024.
2
Reveals an Additional Level of Flowering Regulation in the Shoot Apical Meristem in Response to Light and Increased Temperature in Arabidopsis.揭示了在拟南芥中，光和温度升高对茎尖分生组织开花的调控作用的新层次。
Int J Mol Sci. 2023 Aug 14;24(16):12773. doi: 10.3390/ijms241612773.
3
Polyamine Oxidase-Generated Reactive Oxygen Species in Plant Development and Adaptation: The Polyamine Oxidase-NADPH Oxidase Nexus.
植物发育与适应过程中多胺氧化酶产生的活性氧：多胺氧化酶与NADPH氧化酶的关联
Antioxidants (Basel). 2022 Dec 17;11(12):2488. doi: 10.3390/antiox11122488.
4
Interplay between Proline Metabolism and ROS in the Fine Tuning of Root-Meristem Size in .脯氨酸代谢与活性氧之间的相互作用对[具体植物]根分生组织大小的精细调控
Plants (Basel). 2022 Jun 5;11(11):1512. doi: 10.3390/plants11111512.
5
Regulation of the generation of reactive oxygen species during photosynthetic electron transport.光合电子传递过程中活性氧生成的调控。
Biochem Soc Trans. 2022 Apr 29;50(2):1025-1034. doi: 10.1042/BST20211246.
6
The hidden half comes into the spotlight: Peeking inside the black box of root developmental phases.隐性部分进入聚光灯下：窥视根发育阶段的黑箱内部。
Plant Commun. 2021 Sep 23;3(1):100246. doi: 10.1016/j.xplc.2021.100246. eCollection 2022 Jan 10.
7
Root stem cell niche networks: it's complexed! Insights from Arabidopsis.根干细胞生态位网络：错综复杂！来自拟南芥的新见解。
J Exp Bot. 2021 Oct 13;72(19):6727-6738. doi: 10.1093/jxb/erab272.
8
Peroxisomes as redox-signaling nodes in intracellular communication and stress responses.过氧化物酶体作为细胞内通讯和应激反应中的氧化还原信号节点。
Plant Physiol. 2021 May 27;186(1):22-35. doi: 10.1093/plphys/kiab060.
9
Modulatory Role of Reactive Oxygen Species in Root Development in Model Plant of .活性氧在模式植物根系发育中的调节作用 。 你提供的原文似乎不完整，句末的“of.”后面应该还有具体内容。
Front Plant Sci. 2020 Sep 16;11:485932. doi: 10.3389/fpls.2020.485932. eCollection 2020.
10
Roles of plant retinoblastoma protein: cell cycle and beyond.植物视网膜母细胞瘤蛋白的作用：细胞周期及其他。
EMBO J. 2020 Oct 1;39(19):e105802. doi: 10.15252/embj.2020105802. Epub 2020 Aug 31.