Eiden Rina D, Perry Kristin J, Ivanova Miglena Y, Marcus Rachel C
Department of Psychology, The Pennsylvania State University, University Park, Pennsylvania, USA.
The Social Science Research Institute, The Pennsylvania State University, University Park, Pennsylvania, USA.
Annu Rev Dev Psychol. 2023 Dec;5(1):19-44. doi: 10.1146/annurev-devpsych-120621-043414. Epub 2023 Aug 4.
This is an evaluative review of the field of prenatal substance exposure, with a focus on neurobiological and behavioral outcomes from infancy to young adulthood. We provide an overall evaluation of the state of the field and comment on current conceptual and methodological issues in need of attention. Although there are many studies of prenatal substance exposure, developmental frameworks that incorporate and reflect the lived experiences of children and families have seldom been employed in this field. In addition, although there are some common effects (e.g., on fetal growth) between major substances, there are also unique effects. Thus, we discuss the role of specific substances but note that polysubstance exposure is common, and models and methods used to date may not be sufficient to advance understanding of coexposure or polyexposure effects. We discuss these conceptual and methodological weaknesses and provide suggestions for future directions.
这是一篇关于产前物质暴露领域的评估性综述，重点关注从婴儿期到青年期的神经生物学和行为结果。我们对该领域的现状进行了全面评估，并对当前需要关注的概念和方法问题进行了评论。尽管有许多关于产前物质暴露的研究，但该领域很少采用纳入并反映儿童和家庭生活经历的发展框架。此外，虽然主要物质之间存在一些共同影响（如对胎儿生长的影响），但也有独特的影响。因此，我们讨论了特定物质的作用，但指出多物质暴露很常见，而迄今为止使用的模型和方法可能不足以促进对共同暴露或多暴露影响的理解。我们讨论了这些概念和方法上的弱点，并为未来的方向提供了建议。
