Taravati Shirin, Tehrani Sahar, Khataminia Masoumeh, Rakhshan Vahid
Department of Pediatric Dentistry, School of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Formerly, Department of Dental Anatomy, Azad University of Medical Sciences, Tehran, Iran.
Clin Exp Dent Res. 2025 Oct;11(5):e70187. doi: 10.1002/cre2.70187.
Effects of treatment under general anesthesia versus several sessions of at-office treatment on the transition of caries prevalence from primary to permanent dentitions have not been assessed. Moreover, other gaps exist in the literature.
This 4-group non-randomized clinical trial was performed on 280 children 8-10 years old in 4 groups, including both negative and positive controls: children with a history of caries in primary teeth who were (1) treated routinely in office (n = 60) versus (2) under general anesthesia versus (n = 110) (3) similar children undergoing no treatment versus (positive control, n = 60) (4) children without a history of primary teeth caries (negative caries, n = 50). A clinical assessment was performed to assess dmft (caries and restoration statuses of primary teeth), OHI-S (oral hygiene), and ICDAS indexes (caries and restoration statuses of permanent molars). Data were analyzed (α = 0.05).
There were significant, positive correlations among dmft, caries component of ICDAS, and OHI-S (p-values = 0.000). The dmft scores were significantly different across 4 groups (Kruskal-Wallis p = 0.000), with children treated under general anesthesia followed by in-office treatment and no-treatment positive control group having the highest dmft scores (all Bonferroni-adjusted p-values ≤ 0.013). The ICDAS-caries of the general anesthesia group was significantly greater than the negative control, but also significantly smaller than both positive control and in-office treatment group (all Bonferroni-adjusted p-values ≤ 0.009). Groups were different in terms of OHI-S (Kruskal-Wallis p = 0.000); hygiene was the worst in positive-control and in-office groups, followed by the anesthesia group and the negative control.
Although children who underwent treatment with general anesthesia had the worst dmft scores, treatment under general anesthesia considerably reduced caries of their permanent first molars (as indicated by ICDAS scores) and oral hygiene (as indicated by OHI-S) compared to children who were treated routinely in the office. Primary tooth caries might be a decisive predictor of permanent molar caries formation.
尚未评估全身麻醉下治疗与多次门诊治疗对龋病患病率从乳牙列向恒牙列转变的影响。此外，文献中还存在其他空白。
本4组非随机临床试验对280名8 - 10岁儿童进行了分组，包括阴性和阳性对照：有乳牙龋病史的儿童，其中（1）在门诊常规治疗（n = 60）与（2）在全身麻醉下治疗（n = 110），（3）类似的未接受治疗的儿童（阳性对照，n = 60），（4）无乳牙龋病史的儿童（阴性龋，n = 50）。进行临床评估以评估dmft（乳牙的龋病和修复状况）、OHI - S（口腔卫生）和ICDAS指数（恒牙磨牙的龋病和修复状况）。对数据进行分析（α = 0.05）。
dmft、ICDAS的龋病成分和OHI - S之间存在显著的正相关（p值 = 0.000）。4组之间的dmft评分有显著差异（Kruskal - Wallis p = 0.000），全身麻醉下治疗后再进行门诊治疗的儿童以及未治疗的阳性对照组的dmft评分最高（所有经Bonferroni校正的p值≤0.013）。全身麻醉组的ICDAS - 龋病显著高于阴性对照，但也显著低于阳性对照和门诊治疗组（所有经Bonferroni校正的p值≤0.009）。各组在OHI - S方面存在差异（Kruskal - Wallis p = 0.000）；阳性对照和门诊组的口腔卫生最差，其次是麻醉组和阴性对照。
尽管接受全身麻醉治疗的儿童dmft评分最差，但与在门诊常规治疗的儿童相比，全身麻醉下治疗显著降低了其恒牙第一磨牙的龋病（如ICDAS评分所示）和口腔卫生状况（如OHI - S所示）。乳牙龋病可能是恒牙磨牙龋病形成的决定性预测因素。
