Hosseini Seyede Hanieh, Sharafi Houshmand, Emamjomeh Amirhossein, Nasri Fatemeh, Hosseini Ali, Mardani Sepideh, Moradi Mehran
Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
Probiotics Antimicrob Proteins. 2025 Sep 1. doi: 10.1007/s12602-025-10734-9.
Postbiotics and parabiotics (PP) are innovative concepts in veterinary medicine that have garnered substantial interest owing to their unique properties and potential benefits. PP offers a promising alternative to live bacteria, demonstrating properties such as prebiotic, immunomodulatory, antimicrobial, anti-inflammatory, antioxidant, and anticancer effects, while potentially mitigating some of the common challenges associated with live bacterial applications. PP products are manufactured and commercially employed in livestock, poultry, and pets. Moreover, postbiotic-based commercial products have exhibited a diverse range of beneficial effects including enhanced gut health and microbiota, strengthened immune modulation, stress mitigation, and improved animal production. Moreover, their antimicrobial and anti-inflammatory properties make them viable dietary supplements or additives, potentially replacing antibiotics and addressing the growing concern of antibiotic resistance in the livestock industry. This work reviews the commercial applications of PP in animal nutrition and therapeutics, including in poultry, cattle, sheep, horses, and pet animals. The growing demand for PP products shows that we need to keep researching to find new uses for PP.
后生元和副生物(PP)是兽医学中的创新概念,因其独特的特性和潜在益处而引起了广泛关注。PP为活菌提供了一种有前景的替代方案,具有益生元、免疫调节、抗菌、抗炎、抗氧化和抗癌等作用,同时可能减轻与活菌应用相关的一些常见挑战。PP产品已在牲畜、家禽和宠物中生产并商业化应用。此外,基于后生元的商业产品已展现出多种有益效果,包括改善肠道健康和微生物群、增强免疫调节、缓解应激以及提高动物生产性能。此外,它们的抗菌和抗炎特性使其成为可行的膳食补充剂或添加剂,有可能替代抗生素并解决畜牧业中日益严重的抗生素耐药性问题。本文综述了PP在动物营养和治疗中的商业应用,包括在家禽、牛、羊、马和宠物中的应用。对PP产品不断增长的需求表明,我们需要持续研究以找到PP的新用途。