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Translon: a single term for translated regions.

作者信息

Świrski Michał I, Tierney Jack A S, Albà M Mar, Andreev Dmitry E, Aspden Julie L, Atkins John F, Bassani-Sternberg Michal, Berry Marla J, Biffo Stefano, Boris-Lawrie Kathleen, Borodovsky Mark, Brierley Ian, Brook Matthew, Brunet Marie A, Bujnicki Janusz M, Caliskan Neva, Calviello Lorenzo, Carvunis Anne-Ruxandra, Cate Jamie H D, Cenik Can, Chang Kung Yao, Chen Yiwen, Chothani Sonia, Choudhary Jyoti S, Clark Patricia L, Clauwaert Jim, Cooley Lynn, Dassi Erik, Dean Kellie, Diaz Jean-Jacques, Dieterich Christoph, Dikstein Rivka, Dinman Jonathan D, Dmitriev Sergey E, Dontsova Olga A, Dunham Christine M, Eswarappa Sandeep M, Farabaugh Philip J, Faridi Pouya, Fierro-Monti Ivo, Firth Andrew E, Gatfield David, Gebauer Fátima, Gelfand Mikhail S, Gray Nicola K, Green Rachel, Hill Chris H, Hou Ya-Ming, Hübner Norbert, Ignatova Zoya, Ivanov Pavel, Iwasaki Shintaro, Johnson Rory, Jomaa Ahmad, Jovanovic Marko, Jungreis Irwin, Kellis Manolis, Kieft Jeffrey S, Kochetov Alex V, Koonin Eugene V, Korostelev Andrei A, Kufel Joanna, Kulakovskiy Ivan V, Kurian Leo, Lafontaine Denis L J, Larsson Ola, Loughran Gary, Lukeš Julius, Mariotti Marco, Martens-Uzunova Elena S, Martinez Thomas F, Matsumoto Akinobu, McManus Joel, Medenbach Jan, Melnikov Sergey V, Menschaert Gerben, Merchante Catharina, Mikl Martin, Miller W Allen, Mühlemann Oliver, Namy Olivier, Nedialkova Danny D, Nosek Jozef, Orchard Sandra, Ozretić Petar, Pertea Mihaela, Pervouchine Dmitri D, Romão Luísa, Ron David, Roucou Xavier, Rubtsova Maria P, Ruiz-Orera Jorge, Saghatelian Alan, Salzberg Steven L, Seale Lucia A, Seoighe Cathal, Sergiev Petr V, Shah Premal, Shirokikh Nikolay, Slavoff Sarah A, Sonenberg Nahum, Stasevich Timothy J, Szczesny Roman J, Tamm Tiina, Tchórzewski Marek, Topisirovic Ivan, Tremblay Michel L, Tuller Tamir, Ulitsky Igor, Valášek Leoš Shivaya, Van Damme Petra, Viero Gabriella, Vizcaino Juan Antonio, Vogel Christine, Wallace Edward W J, Weissman Jonathan S, Westhof Eric, Whiffin Nicola, Wilson Daniel N, Xie Zhi, Yewdell Jonathan W, Yordanova Martina M, Yu Chien-Hung, Yurchenko Vyacheslav, Zagrovic Bojan, Valen Eivind, Baranov Pavel V

机构信息

Faculty of Biology, Institute of Genetics and Biotechnology, University of Warsaw, Warsaw, Poland.

School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.

出版信息

Nat Methods. 2025 Sep 1. doi: 10.1038/s41592-025-02810-3.

DOI:10.1038/s41592-025-02810-3
PMID:40890551
Abstract
摘要

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本文引用的文献

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Not all exons are protein coding: Addressing a common misconception.并非所有外显子都编码蛋白质:纠正一个常见的误解。
Cell Genom. 2023 Apr 12;3(4):100296. doi: 10.1016/j.xgen.2023.100296.
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Non-AUG translation initiation in mammals.哺乳动物中的非 AUG 翻译起始。
Genome Biol. 2022 May 9;23(1):111. doi: 10.1186/s13059-022-02674-2.
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Processive Recoding and Metazoan Evolution of Selenoprotein P: Up to 132 UGAs in Molluscs.硒蛋白 P 的连续编码和后生动物进化:软体动物中多达 132 个 UGA。
J Mol Biol. 2019 Nov 8;431(22):4381-4407. doi: 10.1016/j.jmb.2019.08.007. Epub 2019 Aug 20.
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When stop makes sense.何时停止是合理的。
Science. 2016 Dec 2;354(6316):1106. doi: 10.1126/science.aai9060.
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Position-dependent termination and widespread obligatory frameshifting in Euplotes translation.真核游动放线菌翻译中位置依赖性终止和广泛的强制性移码
Nat Struct Mol Biol. 2017 Jan;24(1):61-68. doi: 10.1038/nsmb.3330. Epub 2016 Nov 21.
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Programmed translational bypassing elements in mitochondria: structure, mobility, and evolutionary origin.线粒体中的程序性翻译旁路元件:结构、移动性和进化起源。
Trends Genet. 2015 Apr;31(4):187-94. doi: 10.1016/j.tig.2015.02.010. Epub 2015 Mar 17.
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The leader peptide of yeast gene CPA1 is essential for the translational repression of its expression.酵母基因CPA1的前导肽对其表达的翻译抑制至关重要。
Cell. 1987 Jun 19;49(6):805-13. doi: 10.1016/0092-8674(87)90618-0.
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Cell. 1986 Apr 25;45(2):201-7. doi: 10.1016/0092-8674(86)90384-3.
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Why genes in pieces?为什么基因是断裂的?
Nature. 1978 Feb 9;271(5645):501. doi: 10.1038/271501a0.