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妊娠期间膀胱副神经节瘤:一例报告及文献综述

Urinary bladder paraganglioma in pregnancy: a case report and literature review.

作者信息

Sun Yadong, Chen Lili, Li Yongxiang, Qiao Liang

机构信息

Department of Urology, Weifang People's Hospital, The First Clinical Medical College of Shandong Second Medical University, Weifang, China.

Shangdong Provincial Key Laboratory for Prevention and Treatment of Urological Diseases in Medicine and Health, Weifang, China.

出版信息

Front Med (Lausanne). 2025 Aug 14;12:1527778. doi: 10.3389/fmed.2025.1527778. eCollection 2025.

Abstract

Urinary bladder paragangliomas (UBPs) are rare tumors of chromaffin tissue originating from the sympathetic innervation of the bladder wall. It constitutes less than 0.05% of bladder tumors and 0.7% of all paragangliomas. The occurrence of UBP during pregnancy is extremely rare. Hypertensive disorders of pregnancy due to paraganglioma significantly increase the risk of adverse maternal and fetal outcomes. Herein, we report the case of UBP in a 28-year-old woman at 34 weeks' gestation. The baby was successfully delivered, and bladder tumor was excised via partial cystectomy during the same surgical procedure. In addition, we conducted a literature review of paragangliomas during pregnancy, as there are only a few case reports of such diseases and there is no consensus on standard treatment. This study aims to contribute to the enhancement of the diagnosis and treatment of UBP during pregnancy.

摘要

膀胱副神经节瘤(UBP)是一种起源于膀胱壁交感神经支配的嗜铬组织的罕见肿瘤。它占膀胱肿瘤的比例不到0.05%,占所有副神经节瘤的0.7%。妊娠期间发生UBP极为罕见。由副神经节瘤引起的妊娠高血压疾病显著增加了母婴不良结局的风险。在此,我们报告一例妊娠34周的28岁女性患UBP的病例。婴儿成功分娩,在同一手术过程中通过部分膀胱切除术切除了膀胱肿瘤。此外,我们对妊娠期间的副神经节瘤进行了文献综述,因为关于此类疾病的病例报告很少,且在标准治疗方面尚无共识。本研究旨在有助于提高妊娠期间UBP的诊断和治疗水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a23d/12391184/9ed384df1492/fmed-12-1527778-g001.jpg

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