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整块切除,这会是非肌层浸润性膀胱癌治疗的未来方向吗?介绍我们的技术并对文献进行简要回顾。

En bloc resection, is this the future of non-muscle invasive bladder cancer management? Presentation of our technique and brief review of the literature.

作者信息

Symeonidis Evangelos N, Baniotis Panagiotis, Langas Georgios, Stefanidis Panagiotis, Tsiakaras Stavros, Stratis Michail, Savvides Eliophotos, Bouchalakis Athanasios, Petras Stefanos, Memmos Dimitrios, Anastasiadis Anastasios, Mykoniatis Ioannis, Vakalopoulos Ioannis, Toutziaris Chrysovalantis, Dimitriadis Georgios, Sountoulides Petros

机构信息

First Department of Urology, School of Medicine, "G. Gennimatas" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Department of Pathology, "G. Gennimatas" General Hospital, Thessaloniki, Greece.

出版信息

Urologia. 2023 Feb;90(1):75-79. doi: 10.1177/03915603221093739. Epub 2022 Apr 25.

Abstract

INTRODUCTION

The quality of the initial transurethral resection of bladder tumors (TURBT) plays a key role in accurate local staging thus affecting treatment decision-making and disease prognosis. TURBT is still the gold standard for non-muscle invasive bladder cancer (NMIBC). However, en bloc resection of bladder tumors (ERBT) gradually expanded as a promising alternative to TURBT, aiming to overcome certain inherent limitations of conventional resection. We hereby describe a step-by-step bipolar ERBT technique and briefly review the current trends surrounding the role of various en bloc techniques in the field.

CASE PRESENTATION

We present the case of a 65-year old patient undergoing bipolar ERBT for a single, approximately 2 cm, papillary bladder mass. An experienced urologist completed the procedure within 17 min and without any intra- or postoperative complications. No conversion to TURBT was needed, and an adequate specimen for histological assessment was obtained. The patient made an uneventful recovery, and no recurrence was noted at 12-months.

CONCLUSION

Our initial experience demonstrates that ERBT via bipolar current is relatively quick, safe, and reliable. Prospective comparative clinical trials will examine its efficacy, and long-term oncological superiority in managing NMIBC.

摘要

引言

膀胱肿瘤初次经尿道切除术(TURBT)的质量在准确的局部分期中起着关键作用,从而影响治疗决策和疾病预后。TURBT仍是非肌层浸润性膀胱癌(NMIBC)的金标准。然而,整块切除膀胱肿瘤(ERBT)作为TURBT一种有前景的替代方法逐渐兴起,旨在克服传统切除术的某些固有局限性。在此,我们描述一种分步双极ERBT技术,并简要回顾该领域中各种整块切除技术作用的当前趋势。

病例报告

我们报告一例65岁患者,因单个约2 cm的乳头状膀胱肿物接受双极ERBT。一位经验丰富的泌尿外科医生在17分钟内完成手术,术中及术后均无并发症。无需转为TURBT,且获得了足够用于组织学评估的标本。患者恢复顺利,12个月时未发现复发。

结论

我们的初步经验表明,双极电流ERBT相对快速、安全且可靠。前瞻性比较临床试验将检验其在管理NMIBC中的疗效及长期肿瘤学优势。

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