Ehsan Noor, Batool Maha, Farooka Imran, Malik Mahmood N
Internal Medicine, Gulab Devi Teaching Hospital, Lahore, PAK.
Internal Medicine, Gulab Devi Teaching Hospital, Al-Aleem Medical College, Lahore, PAK.
Cureus. 2025 Jul 30;17(7):e89072. doi: 10.7759/cureus.89072. eCollection 2025 Jul.
Pulmonary and extrapulmonary tuberculosis impose a major load of chronic disease burden. Lymph node and pleural tuberculosis are the most common types of extrapulmonary tuberculosis. Isolated hoarseness of voice is a rare presenting feature of lymph node tuberculosis. We present the case of a young girl who presented to us with the complaint of hoarseness of voice for two months. A contrast-enhanced CT of the neck and chest revealed bilateral cervical and mediastinal lymphadenopathy encroaching on the aortopulmonary window. A 70-degree rigid endoscopy revealed left vocal cord paralysis. A cervical lymph node excision biopsy showed necrotizing granulomatous inflammation and Langhan-type giant cells. The diagnosis was confirmed by culture on Löwenstein-Jensen medium and drug susceptibility testing, which identified sensitive to all first-line antitubercular drugs. She was put on weight-based antitubercular therapy, after which her voice showed improvement, and she gained four kilograms. We present this case to highlight the importance of being familiar with uncommon presentations of common diseases, particularly in areas of high disease endemicity, to allow for timely diagnosis and treatment.
肺结核和肺外结核带来了重大的慢性疾病负担。淋巴结结核和胸膜结核是肺外结核最常见的类型。孤立性声音嘶哑是淋巴结结核罕见的临床表现。我们报告了一名年轻女孩的病例,她因声音嘶哑两个月前来就诊。颈部和胸部的增强CT显示双侧颈部和纵隔淋巴结肿大,侵犯了主动脉肺动脉窗。70度硬质内镜检查显示左侧声带麻痹。颈部淋巴结切除活检显示坏死性肉芽肿性炎症和朗汉斯型巨细胞。通过罗氏培养基培养和药敏试验确诊,结果显示对所有一线抗结核药物敏感。她接受了基于体重的抗结核治疗,之后声音有所改善,体重增加了4公斤。我们展示这个病例是为了强调熟悉常见疾病的罕见表现的重要性,特别是在疾病高发地区,以便能够及时诊断和治疗。