Huma Huria, Subahi Doaa, Rajendran Monica, Karim Nawazish
Respiratory Medicine, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Cardiology, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Cureus. 2025 Jul 31;17(7):e89186. doi: 10.7759/cureus.89186. eCollection 2025 Jul.
A 24-year-old British Indian male experienced a severe and complex course of cavitating pneumonia caused by a rare co-infection with , , and a non- species. He initially presented with symptoms of community-acquired pneumonia and was treated with antibiotics and subsequently discharged. Four days later, he re-presented with hemoptysis, hypoxia, and sepsis, requiring intensive care admission. Imaging revealed extensive cavitating lesions in the right lower lobe, empyema, pneumothorax, and a Rasmussen aneurysm. Management included 24 h in the intensive care unit, multiple chest drains, embolization of the aneurysm, and a three-month course of combined antibiotic, antifungal, and antituberculous therapy. Comprehensive immunological workup, including HIV testing, was negative, confirming the patient's immunocompetent status. This case highlights the extreme rarity of such a multifaceted pulmonary co-infection in a young, otherwise healthy individual, and underscores the importance of early identification and aggressive management of concurrent infections and rare but life-threatening complications such as Rasmussen aneurysm and invasive fungal co-infection.
一名24岁的英裔印度男性经历了由罕见的 、 和一种非 菌种共同感染引起的严重且复杂的空洞性肺炎病程。他最初表现为社区获得性肺炎症状，接受抗生素治疗后出院。四天后，他再次出现咯血、缺氧和脓毒症，需要入住重症监护病房。影像学检查显示右下叶有广泛的空洞性病变、脓胸、气胸和一个拉斯姆森动脉瘤。治疗措施包括在重症监护病房治疗24小时、多次胸腔引流、动脉瘤栓塞以及为期三个月的联合抗生素、抗真菌和抗结核治疗。包括艾滋病毒检测在内的全面免疫学检查结果为阴性，证实患者免疫功能正常。该病例凸显了在一名原本健康的年轻人中出现这种多方面肺部合并感染的极端罕见性，并强调了早期识别以及积极处理并发感染和诸如拉斯姆森动脉瘤和侵袭性真菌合并感染等罕见但危及生命的并发症的重要性。
