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在医学领域实现全系统变革:实施科学在实现规模效应和推广应用方面的作用。

Creating system-wide change in medicine: The role of implementation science in achieving scale and adoption.

作者信息

Barry Simon, Davies Chris

机构信息

School of Medicine, Cardiff University, Cardiff, UK.

Institute for Future Studies, Stockholm, Sweden.

出版信息

Future Healthc J. 2025 Jul 23;12(3):100452. doi: 10.1016/j.fhj.2025.100452. eCollection 2025 Sep.

DOI:10.1016/j.fhj.2025.100452
PMID:40896305
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12395526/
Abstract

Delivering meaningful change in healthcare is less about new discoveries and more about ensuring adoption at scale of what is already known to work. Implementation science (IS) studies the methods that support systematic uptake of evidence-based practices into routine care. Yet traditional strategies - like policy mandates, staff training alone, or the passive spread of information - often fail to deliver sustained change. This paper introduces the foundational principles of IS, critiques conventional approaches, and shares lessons learned from national-scale digital implementation efforts in Wales. Key IS enablers, including leadership, stakeholder alignment, readiness and feedback systems, are described in practical terms. We aim to make IS accessible for healthcare leaders and clinicians seeking to reduce variation and embed innovation at scale.

摘要

在医疗保健领域实现有意义的变革,与其说是关于新发现,不如说是关于确保大规模采用已知有效的方法。实施科学(IS)研究支持将循证实践系统纳入常规护理的方法。然而,传统策略,如政策指令、单纯的员工培训或信息的被动传播,往往无法带来持续的变革。本文介绍了实施科学的基本原则,对传统方法进行了批判,并分享了在威尔士全国范围内数字实施工作中吸取的经验教训。从实际角度描述了关键的实施科学推动因素,包括领导力、利益相关者协调、准备情况和反馈系统。我们的目标是让寻求减少差异并大规模嵌入创新的医疗保健领导者和临床医生能够理解实施科学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd45/12395526/8c1b9cf0c1e8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd45/12395526/8c1b9cf0c1e8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd45/12395526/8c1b9cf0c1e8/gr1.jpg

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本文引用的文献

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Creating expert patients: outcomes from a national digital therapeutic approach for people with asthma in Wales.打造专业患者:威尔士针对哮喘患者的全国性数字治疗方法的成果
NPJ Prim Care Respir Med. 2025 Jun 9;35(1):29. doi: 10.1038/s41533-025-00433-x.
2
Trends in low global warming potential inhaler prescribing: A UK-wide cohort comparison from 2018-2024.低全球变暖潜能值吸入器处方趋势:2018 - 2024年全英国队列比较
NPJ Prim Care Respir Med. 2025 Feb 20;35(1):9. doi: 10.1038/s41533-025-00415-z.
3
Ten years of implementation outcomes research: a scoping review.
十年实施结果研究:范围综述。
Implement Sci. 2023 Jul 25;18(1):31. doi: 10.1186/s13012-023-01286-z.
4
Strategies to promote guideline adoption: lessons learned from the implementation of a national COVID-19 hospital guideline across NHS Wales.促进指南采用的策略:从威尔士国民保健服务体系(NHS Wales)实施国家新冠病毒医院指南中吸取的经验教训。
Future Healthc J. 2022 Nov;9(3):262-267. doi: 10.7861/fhj.2022-0028.
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Value based healthcare.基于价值的医疗保健。
BMJ. 2017 Jan 27;356:j437. doi: 10.1136/bmj.j437.
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A refined compilation of implementation strategies: results from the Expert Recommendations for Implementing Change (ERIC) project.实施策略的精准汇编:实施变革专家建议(ERIC)项目的成果
Implement Sci. 2015 Feb 12;10:21. doi: 10.1186/s13012-015-0209-1.
7
The dynamic sustainability framework: addressing the paradox of sustainment amid ongoing change.动态可持续性框架:应对持续变化中的维持悖论。
Implement Sci. 2013 Oct 2;8:117. doi: 10.1186/1748-5908-8-117.
8
Effects of pay for performance in health care: a systematic review of systematic reviews.绩效薪酬对医疗保健的影响:系统评价的系统评价。
Health Policy. 2013 May;110(2-3):115-30. doi: 10.1016/j.healthpol.2013.01.008. Epub 2013 Feb 4.
9
Large-system transformation in health care: a realist review.医疗保健中的大系统转型:一个现实主义的综述。
Milbank Q. 2012 Sep;90(3):421-56. doi: 10.1111/j.1468-0009.2012.00670.x.
10
The answer is 17 years, what is the question: understanding time lags in translational research.答案是 17 年,问题是:理解转化研究中的时间滞后。
J R Soc Med. 2011 Dec;104(12):510-20. doi: 10.1258/jrsm.2011.110180.