Saharti Samah N, Almutairi Fawaz M
From the Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Saudi Med J. 2025 Sep;46(9):985-991. doi: 10.15537/smj.2025.46.9.20250209.
To analyze the trends, histopathological characteristics, and demographic distribution of genitourinary (GU) tumors at a major academic center in Jeddah, Saudi Arabia, over a 16-year period (2007-2023).
A retrospective review of electronic medical records was conducted, including all histologically confirmed cases of GU tumors. Data on patient demographics, tumor type, and histopathological findings were extracted and analyzed using descriptive and inferential statistical methods.
A total of 1,791 GU tumor cases were identified. Bladder cancer was the most prevalent (42%), followed by prostate cancer (21%) and renal cell carcinoma (21%). Testicular and ureteral tumors were less common, with scrotal and penile malignancies being rare (<1%). The mean age at diagnosis varied significantly, with prostate and bladder cancers occurring predominantly in older patients, while testicular tumors were diagnosed at a younger age. A significant rise in kidney and bladder cancer diagnoses was observed, potentially linked to improved screening and environmental factors.
This study provides valuable insights into the epidemiological trends of GU tumors in Saudi Arabia, emphasizing the need for early detection and targeted screening. Further research is needed to explore contributing factors and optimize treatment approaches.
分析沙特阿拉伯吉达一家主要学术中心16年期间（2007 - 2023年）泌尿生殖系统（GU）肿瘤的发病趋势、组织病理学特征及人口统计学分布。
对电子病历进行回顾性研究，纳入所有经组织学确诊的GU肿瘤病例。提取患者人口统计学、肿瘤类型及组织病理学检查结果等数据，并采用描述性和推断性统计方法进行分析。
共识别出1791例GU肿瘤病例。膀胱癌最为常见（42%），其次是前列腺癌（21%）和肾细胞癌（21%）。睾丸和输尿管肿瘤较少见，阴囊和阴茎恶性肿瘤罕见（<1%）。诊断时的平均年龄差异显著，前列腺癌和膀胱癌主要发生于老年患者，而睾丸肿瘤多在较年轻患者中诊断出。观察到肾癌和膀胱癌诊断病例显著增加，这可能与筛查改善及环境因素有关。
本研究为沙特阿拉伯GU肿瘤的流行病学趋势提供了有价值的见解，强调了早期检测和针对性筛查的必要性。需要进一步研究以探索相关因素并优化治疗方法。
