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[缺血性心脏病中人类单核细胞的胆固醇酯酶活性]

[Cholesterol esterase activity of human monocytes in ischemic heart disease].

作者信息

Medvedeva I N, Dolgov A V, Nikitin Iu P

出版信息

Ter Arkh. 1985;57(12):50-2.

PMID:4089769
Abstract

The comparison on the effect of atherosclerotic lesion of the vascular system on changes in the activity of human blood mononuclear cell lysosomal and cytoplasmic cholesterolesterases showed that these changes were of diverse nature an increase in lysosomal cholesterolesterase activity and a decrease in cytoplasmatic activity. It can be accounted for be a different role of acid and alkaline cholesteroesterases in cell cholesterol metabolism and by different mechanisms of the regulation of these enzymes.

摘要

对血管系统动脉粥样硬化病变对人血单核细胞溶酶体和细胞质胆固醇酯酶活性变化的影响进行比较,结果表明这些变化具有不同的性质,即溶酶体胆固醇酯酶活性增加,细胞质活性降低。这可以归因于酸性和碱性胆固醇酯酶在细胞胆固醇代谢中的不同作用以及这些酶的不同调节机制。

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