Lou Jia-Qi, Hu Zhi-Wei, Liu Kun, A Ru-La, Fang Hao-Yu
Department of Surgery, Inner Mongolia Medical University, Hohhot, China.
Department of Hepatobiliary Surgery, Inner Mongolia People's Hospital, Hohhot, China.
Front Oncol. 2025 Aug 18;15:1642467. doi: 10.3389/fonc.2025.1642467. eCollection 2025.
Carcinosarcoma of the common bile duct is an exceedingly rare and highly aggressive malignancy with uncertain therapeutic outcomes. We present a case of a 70-year-old Asian female presenting with progressive jaundice. Contrast-enhanced computed tomography (CT) identified a tumor in the common bile duct. The patient underwent successful radical pancreaticoduodenectomy, and postoperative histopathological analysis confirmed carcinosarcoma with predominant sarcomatoid differentiation. This report underscores the diagnostic challenges and therapeutic considerations for this rare entity, emphasizing the critical role of pathological confirmation.
胆管癌肉瘤是一种极其罕见且侵袭性很强的恶性肿瘤,治疗结果尚不确定。我们报告一例70岁亚洲女性患者,表现为进行性黄疸。增强计算机断层扫描(CT)发现胆管有一个肿瘤。患者成功接受了根治性胰十二指肠切除术,术后组织病理学分析证实为以肉瘤样分化为主的癌肉瘤。本报告强调了这种罕见疾病的诊断挑战和治疗考量,突出了病理确诊的关键作用。