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血小板减少症小鼠肾脏中H3-亮氨酸的掺入。尝试证明血小板生成素的产生。

Incorporation of H3-leucine in the mouse kidney in thrombocytopenia. Attempt to demonstrate thrombopoietin production.

作者信息

Krizsa F, Cserháti I, Halász N, Joó F

出版信息

Acta Haematol. 1977;58(3):134-7. doi: 10.1159/000207819.

DOI:10.1159/000207819
PMID:409027
Abstract

Light and dark field autoradiography of semithin sections prepared 6 h after a treatment with APS showed that the incorporation of H3-leucine into the cells of the convoluted tubules of the kidney was increased in mice. There was no difference in the H3-leucine incorporation in the liver, either in thrombocytopenic or in untreated animals. The increased incorporation of leucine in the kidney in APS-induced thrombocytopenia showed coincidence with increased thrombopoietin production.

摘要

用APS处理6小时后制备的半薄切片的明场和暗场放射自显影显示,小鼠肾脏曲管细胞中H3-亮氨酸的掺入增加。在血小板减少的动物或未处理的动物中,肝脏中H3-亮氨酸的掺入没有差异。APS诱导的血小板减少症中肾脏中亮氨酸掺入的增加与血小板生成素产生的增加一致。

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