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[酮替芬治疗慢性荨麻疹。对治疗困难病程的开放性研究]

[Ketotifen treatment of chronic urticaria. An open study of therapeutically difficult courses].

作者信息

Taube K M, Wozniak K D, Lässig W

出版信息

Z Hautkr. 1985 Dec 1;60(23):1878, 1881-2, 1885.

PMID:4090577
Abstract

21 patients suffering from chronic urticaria were treated with Ketotifen (2 X 1 mg/d) for 4 weeks. The suppression of weals and pruritus, the side effects in comparison with antihistamines, as well as the effect after finishing therapy have been studied. Ketotifen has a good suppressing effect on weals and pruritus. The general tolerance of the preparation is good, as well. Thus Ketotifen may be regarded as an additional possibility concerning treatment of chronic urticaria.

摘要

21例慢性荨麻疹患者接受了酮替芬治疗(2×1毫克/天),疗程4周。研究了对风团和瘙痒的抑制作用、与抗组胺药相比的副作用以及治疗结束后的效果。酮替芬对风团和瘙痒有良好的抑制作用。该制剂的总体耐受性也良好。因此,酮替芬可被视为治疗慢性荨麻疹的另一种选择。

相似文献

1
[Ketotifen treatment of chronic urticaria. An open study of therapeutically difficult courses].[酮替芬治疗慢性荨麻疹。对治疗困难病程的开放性研究]
Z Hautkr. 1985 Dec 1;60(23):1878, 1881-2, 1885.
2
[Treatment of chronic urticaria with ketotifen].
Allerg Immunol (Paris). 1986 Sep;18(7):33-5.
3
[Chronic urticaria. Treatment with ketotifen].[慢性荨麻疹。用酮替芬治疗]
Med Cutan Ibero Lat Am. 1982;10(5):339-42.
4
[Ketotifen in the treatment of chronic urticaria and angioneurotic edema].[酮替芬治疗慢性荨麻疹和血管神经性水肿]
Allergol Immunopathol (Madr). 1984 Jan-Feb;12(1):19-27.
5
[Effect of ketotifen in urticaria factitia and urticaria cholinergica in a crossover double-blind trial].[酮替芬在人工性荨麻疹和胆碱能性荨麻疹交叉双盲试验中的作用]
Hautarzt. 1985 Sep;36(9):509-11.
6
Clinical evaluation of ketotifen for chronic urticaria: multicenter double-blind comparative study with clemastine.酮替芬治疗慢性荨麻疹的临床评估:与氯马斯汀的多中心双盲对照研究
Ann Allergy. 1989 Apr;62(4):322-5.
7
Effect of ketotifen treatment on cold-induced urticaria.
Ann Allergy. 1985 Dec;55(6):840-3.
8
[Clinical effectiveness and prospects for using zaditen (ketotifen) in the therapy of allergic dermatoses].[扎迪特(酮替芬)在过敏性皮肤病治疗中的临床疗效及应用前景]
Vestn Dermatol Venerol. 1987(4):52-5.
9
Treatment of chronic urticaria with ketotifen.
Arch Dermatol. 1997 Feb;133(2):147-9.
10
[The use of zaditen in the combined treatment of allergic skin diseases in children].[扎迪特(zaditen)在儿童过敏性皮肤病联合治疗中的应用]
Vestn Dermatol Venerol. 1989(7):43-7.

引用本文的文献

1
Ketotifen in the management of chronic urticaria: resurrection of an old drug.酮替芬在慢性荨麻疹治疗中的应用:一种老药的复兴
Ann Allergy Asthma Immunol. 2013 Dec;111(6):433-6. doi: 10.1016/j.anai.2013.10.003. Epub 2013 Oct 25.