Rahlf G
Z Kardiol. 1985;74 Suppl 7:9-16.
The average heart weight increases up to the 9th decade. An existence of senile atrophy is not confirmed. Various morphological abnormalities of the heart in the elderly can be found during the course of life--polypathy of the heart. The number of these changes increases on average in each heart linearly with age. In polypathy of the heart the abnormalities which have functional consequences, such as stenosing coronary sclerosis, small vessel disease, heart hypertrophy, calcification of mitral ring and/or the aortic valves, as well as a cardiac amyloidosis are of the utmost importance. The polypathy of the heart in the elderly increases its vulnerability and may lead to a latent or manifest heart insufficiency. The law of polypathy is not only valid for the heart, but also for the whole organism.
平均心脏重量在90岁之前会不断增加。未证实存在老年性萎缩。在老年人的一生中,可发现心脏存在各种形态学异常——心脏息肉病。这些变化的数量平均在每个心脏中随年龄呈线性增加。在心脏息肉病中,具有功能后果的异常,如狭窄性冠状动脉硬化、小血管疾病、心脏肥大、二尖瓣环和/或主动脉瓣钙化以及心脏淀粉样变性最为重要。老年人的心脏息肉病会增加其易损性,并可能导致潜在或明显的心功能不全。息肉病规律不仅适用于心脏,也适用于整个机体。