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[与衰老相关的心血管系统的形态学和功能方面:“衰老心脏”存在吗?]

[Morphological and functional aspects of the cardiovascular system related to aging: does "aging heart" exist?].

作者信息

Cafagna D, Ponte E

机构信息

I Divisione di Medicina Generale, Azienda per i Servizi Sanitari n. 1 Triestina, Trieste.

出版信息

Minerva Med. 1997 Dec;88(12):491-500.

PMID:9540778
Abstract

Elderly people are the most rapid growing segment of society, and heart disease is the most common cause of death in this population. The aging process is associated with anatomic and physiologic alterations in the cardiovascular system; consequently, the manifestations of disease in the geriatric population differ from those involving younger patients. To formulate diagnosis of "aging heart" in older patient may be difficult, because of atypical symptoms or of the acceptance of symptoms as manifestations of old age. Aging is, moreover, often associated with a decline in physical activity, which may result in cardiovascular "deconditioning". The treatment strategy is the same as in younger patients, but the higher incidence of adverse effects and complications demands special awareness. In this article we discuss about age-related structural and functional changes that occur in the cardiovascular system, including changes in the heart muscle, valves, conduction system and major arteries.

摘要

老年人是社会中增长最快的群体,而心脏病是该人群最常见的死因。衰老过程与心血管系统的解剖学和生理学改变相关;因此,老年人群中疾病的表现与年轻患者不同。由于症状不典型或因将症状视为老年的表现,在老年患者中做出“老年心脏”的诊断可能很困难。此外,衰老常与体力活动减少有关,这可能导致心血管“失健”。治疗策略与年轻患者相同,但不良反应和并发症的发生率较高需要特别关注。在本文中,我们讨论心血管系统中发生的与年龄相关的结构和功能变化,包括心肌、瓣膜、传导系统和主要动脉的变化。

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