Cottle Rachel M, Wolf S Tony, Kenney W Larry
Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, United States.
Department of Kinesiology, University of Georgia, Athens, Georgia, United States.
J Appl Physiol (1985). 2025 Sep 1;139(3):832-838. doi: 10.1152/japplphysiol.00323.2025. Epub 2025 Sep 4.
The increase in duration, severity, and frequency of extreme heat will have a profound detrimental impact on human health, as extreme heat is the deadliest weather-related event around the world. At the same time, the population of older (>65 yr) adults is rapidly expanding. The exaggerated heat, coupled with an aging population, increases the number of people at risk during environmental extremes. During heat waves, cardiovascular events and complications secondary to elevated core temperatures are the leading cause of increased morbidity and mortality among older adults. Seminal work demonstrates an impaired cardiovascular response to elevated core and skin temperatures in older adults, resulting in an attenuated capacity to lose heat coupled with increased cardiac strain, in support of the epidemiological data. Here, we review the impact of heat stress on the aged cardiovascular system and highlight the question: "In what specific environments does an increased cardiovascular strain begin to occur in older adults?"
极端高温天气在持续时间、严重程度和发生频率上的增加,将对人类健康产生深远的不利影响,因为极端高温是全球最致命的与天气相关的事件。与此同时,老年人(年龄>65岁)的数量正在迅速增长。酷热加上人口老龄化,增加了极端环境下处于危险中的人数。在热浪期间,心血管事件以及核心体温升高引发的并发症,是老年人发病率和死亡率上升的主要原因。开创性研究表明,老年人对核心体温和皮肤温度升高的心血管反应受损,导致散热能力减弱以及心脏负荷增加,这与流行病学数据相符。在此,我们综述热应激对老年心血管系统的影响,并着重提出这个问题:“在哪些特定环境下,老年人心血管负荷开始增加?”