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Reaffirming the value of model organisms in training scientific minds.

作者信息

Yang Miaoling, Du Zhuo

机构信息

Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.

University of Chinese Academy of Sciences, Beijing, China.

出版信息

Nat Cell Biol. 2025 Sep 4. doi: 10.1038/s41556-025-01754-2.

DOI:10.1038/s41556-025-01754-2
PMID:40908352
Abstract
摘要

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Dev Biol. 2025 Sep;525:270-281. doi: 10.1016/j.ydbio.2025.05.028. Epub 2025 May 31.
2
Engaging students in a genetics course-based undergraduate research experience utilizing in hybrid learning to explore human disease gene variants.让学生参与基于遗传学课程的本科研究体验，利用混合式学习来探索人类疾病基因变异。
J Microbiol Biol Educ. 2023 Nov 16;24(3). doi: 10.1128/jmbe.00078-23. eCollection 2023 Dec.
3
Integrating non-mammalian model organisms in the diagnosis of rare genetic diseases in humans.
将非哺乳动物模式生物应用于人类罕见遗传病的诊断
Nat Rev Genet. 2024 Jan;25(1):46-60. doi: 10.1038/s41576-023-00633-6. Epub 2023 Jul 25.
4
The great small organisms of developmental genetics: Caenorhabditis elegans and Drosophila melanogaster.发育遗传学中的伟大小生物：秀丽隐杆线虫和黑腹果蝇。
Dev Biol. 2022 May;485:93-122. doi: 10.1016/j.ydbio.2022.02.013. Epub 2022 Mar 2.
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A 4D single-cell protein atlas of transcription factors delineates spatiotemporal patterning during embryogenesis.一个 4D 单细胞转录因子蛋白质图谱描绘了胚胎发生过程中的时空模式。
Nat Methods. 2021 Aug;18(8):893-902. doi: 10.1038/s41592-021-01216-1. Epub 2021 Jul 26.
6
Fruit flies in biomedical research.生物医学研究中的果蝇。
Genetics. 2015 Mar;199(3):639-53. doi: 10.1534/genetics.114.171785. Epub 2015 Jan 26.
7
The zebrafish issue of Development.《发育》杂志的斑马鱼特刊。
Development. 2012 Nov;139(22):4099-103. doi: 10.1242/dev.085217.
8
Plant biologists fear for cress project.植物生物学家对水芹项目感到担忧。
Nature. 2010 Mar 11;464(7286):154. doi: 10.1038/464154a.
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Animal models of human disease: zebrafish swim into view.人类疾病的动物模型：斑马鱼进入视野。
Nat Rev Genet. 2007 May;8(5):353-67. doi: 10.1038/nrg2091.
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Profile of C. David Allis.C. 大卫·艾利斯简介。
Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6425-7. doi: 10.1073/pnas.0602256103. Epub 2006 Apr 17.