基于晨型-夜型偏好的癌症患者昼夜节律评估：一项横断面研究。
Cancer Patients Circadian Rhythm Assessment Based on Morningness-Eveningness Preference: A Cross-Sectional Study.
作者信息
Daftari Ghazal, Abbaszadeh Mahsa, Karimpour Reyhan Sahar, Khajavirad Nasim
机构信息
Department of Internal Medicine Imam Khomeini Hospital Complex Tehran University of Medical Sciences Tehran Iran.
Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, Imam Khomeini Hospital Complex Tehran University of Medical Sciences Tehran Iran.
出版信息
Health Sci Rep. 2025 Sep 3;8(9):e71210. doi: 10.1002/hsr2.71210. eCollection 2025 Sep.
BACKGROUND AND AIM
The circadian rhythm regulates various physiological processes, including sleep-wake cycle, cell division and cancer development. This study aimed to investigate circadian rhythm patterns in cancer patients.
METHODS
In this cross-sectional study, 150 cancer patients admitted to the hospital enrolled the study during the fall of 2022. The demographic characteristics of patients were collected using a checklist. Patients also completed a morningness-eveningness questionnaire (MEQ). Utilizing Analysis of Variance (ANOVA) and Fisher's exact test, circadian rhythm types with continuous and categorical variables were compared.
RESULTS
The mean age of the study's participants was 49.83 ± 14.53 years. A total of 82.7% ( = 124) had non-hematological cancers, and breast cancer was the most prevalent type of cancer among patients (23.3%). The MEQ of the patients studied ranged from 41 to 74, with a mean score of 56.6 ± 6.34.
CONCLUSION
According to the findings of this study, the circadian rhythm is distributed normally among the participants.
背景与目的
昼夜节律调节包括睡眠-清醒周期、细胞分裂和癌症发展在内的各种生理过程。本研究旨在调查癌症患者的昼夜节律模式。
方法
在这项横断面研究中，2022年秋季入住该医院的150名癌症患者参与了研究。使用检查表收集患者的人口统计学特征。患者还完成了晨型-夜型问卷（MEQ）。利用方差分析（ANOVA）和费舍尔精确检验，对连续变量和分类变量的昼夜节律类型进行了比较。
结果
研究参与者的平均年龄为49.83±14.53岁。共有82.7%（n = 124）患有非血液系统癌症，乳腺癌是患者中最常见的癌症类型（23.3%）。所研究患者的MEQ范围为41至74，平均得分为56.6±6.34。
结论
根据本研究的结果，昼夜节律在参与者中呈正态分布。
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