丙酮丁醇梭菌耐丁醇突变体的分离与鉴定
Isolation and characterization of butanol-resistant mutants of Clostridium acetobutylicum.
作者信息
Hermann M, Fayolle F, Marchal R, Podvin L, Sebald M, Vandecasteele J P
出版信息
Appl Environ Microbiol. 1985 Nov;50(5):1238-43. doi: 10.1128/aem.50.5.1238-1243.1985.
Abstract
In a wild-type strain of Clostridium acetobutylicum isolated from soil, solvent production appeared limited by butanol toxicity. Butanol-resistant mutants have been obtained which produced significantly higher solvent concentrations (about 30%) than the wild-type strain. Some other physiological differences were observed between a selected resistant mutant and the wild-type strain at the level of solvent resistance and sporulation.
摘要
从土壤中分离出的野生型丙酮丁醇梭菌菌株中，溶剂生产似乎受到丁醇毒性的限制。已经获得了抗丁醇突变体，其产生的溶剂浓度比野生型菌株显著更高（约30%）。在溶剂抗性和孢子形成水平上，观察到选定的抗性突变体与野生型菌株之间存在一些其他生理差异。
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