Pasquino A M, Tebaldi L, Cioschi L, Cives C, Finocchi G, Maciocci M, Mancuso G, Boscherini B
Arch Dis Child. 1985 Dec;60(12):1180-2. doi: 10.1136/adc.60.12.1180.
Follow up of 40 girls with premature thelarche showed that where this disorder occurred before age 2 years it usually regressed completely, thus representing a transient and isolated phenomenon. Premature thelarche after age 2 years persisted more frequently, however, and represented the first sign of sexual development, generally leading to simple early puberty.
对40例乳房过早发育女童的随访表明，若该病症在2岁前出现，通常会完全消退，因此这是一种短暂且孤立的现象。然而，2岁后出现的乳房过早发育更常持续存在，且是性发育的首个迹象，通常会导致单纯性性早熟。
