性早熟：40名女孩的随访研究。自然病史及内分泌检查结果
Premature thelarche: a follow up study of 40 girls. Natural history and endocrine findings.
作者信息
Pasquino A M, Tebaldi L, Cioschi L, Cives C, Finocchi G, Maciocci M, Mancuso G, Boscherini B
出版信息
Arch Dis Child. 1985 Dec;60(12):1180-2. doi: 10.1136/adc.60.12.1180.
Abstract
Follow up of 40 girls with premature thelarche showed that where this disorder occurred before age 2 years it usually regressed completely, thus representing a transient and isolated phenomenon. Premature thelarche after age 2 years persisted more frequently, however, and represented the first sign of sexual development, generally leading to simple early puberty.
摘要
对40例乳房过早发育女童的随访表明，若该病症在2岁前出现，通常会完全消退，因此这是一种短暂且孤立的现象。然而，2岁后出现的乳房过早发育更常持续存在，且是性发育的首个迹象，通常会导致单纯性性早熟。
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本文引用的文献
1
Premature thelarche. Natural history and etiologic investigation.性早熟。自然病史与病因学研究。
Am J Dis Child. 1981 Aug;135(8):743-5.
2
Hypothalamic-pituitary-gonadotropic function in girls with premature thelarche.性早熟女童的下丘脑-垂体-促性腺功能
Arch Dis Child. 1980 Dec;55(12):941-4. doi: 10.1136/adc.55.12.941.
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[Isolated breast prematurity in young girls].
Arch Fr Pediatr. 1983 Aug-Sep;40(7):549-52.
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Premature thelarche--natural history and sex hormone secretion in 68 girls.性早熟——68例女童的自然病史及性激素分泌情况
Acta Paediatr Scand. 1984 Nov;73(6):756-62. doi: 10.1111/j.1651-2227.1984.tb17771.x.
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Cervical and vaginal cytology in the child and adolescent.儿童及青少年的宫颈和阴道细胞学检查
Pediatr Clin North Am. 1972 Aug;19(3):547-57. doi: 10.1016/s0031-3955(16)32738-9.
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Responsivity of pituitary gonadotropes to luteinizing hormone-releasing factor in idiopathic precocious puberty, precocious thelarche, precocious adrenarche, and in patients treated with medroxyprogesterone acetate.特发性性早熟、乳房过早发育、肾上腺功能过早初现以及接受醋酸甲羟孕酮治疗的患者中垂体促性腺细胞对促黄体生成素释放因子的反应性。
Pediatr Res. 1975 Feb;9(2):111-6. doi: 10.1203/00006450-197502000-00011.
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