Wong Caitlyn E, Luther Madison N, Scatena Avery, Koike Seiji, Novak Melissa, Elliott Jonathan E, Iliff Jeffrey J, Lim Miranda M, Kosderka Emily, Piantino Juan
Department of Pediatrics, Division of Child Neurology, Doernbecher Children's Hospital, Oregon Health and Science University, Portland, OR, United States.
Department of Biostatistics, Oregon Health & Science University, Portland, OR, United States.
Sleep Adv. 2025 Jul 26;6(3):zpaf048. doi: 10.1093/sleepadvances/zpaf048. eCollection 2025.
Conduct a multidimensional analysis of sleep perception, objective sleep, and neuropsychiatric wellbeing in individuals with subacute concussion compared to controls.
Thirty-one recently concussed individuals completed the Pittsburgh Sleep Quality Index, Insomnia Severity Index, and Patient-Report Outcomes Measurement Information System measures of depression, anxiety, stress, and cognitive function. Concussion symptom severity scores (Sports Concussion Assessment Tool) were obtained from participants' health records. Sleep parameters were derived from at least 7 days of monitoring with the Emfit QS device (total sleep time [TST], time in bed, sleep onset latency, sleep efficiency, wake after sleep onset). Data were compared to 19 controls using parametric or non-parametric tests for independence ( = 0.05). Pearson correlations and linear mixed models assessed relationships between data modalities.
Concussed individuals reported worse sleep and had lower sleep efficiency, longer time in bed, and greater sleep onset latency than controls ( < .05). Patient-Report Outcomes Measurement Information System symptom scores moderated these relationships at significant or near-significant levels. Controls demonstrated agreement between reported and measured sleep (for TST: = 0.52; = .023) and a positive relationship between sleep dissatisfaction and wake after sleep onset ( < .05). These relationships were not observed in individuals with concussion. Moreover, individuals with greater discrepancy between reported and measured sleep scored higher on Sports Concussion Assessment Tool concussion symptom inventories ( = 9.5/h; = .007; = .022; Total = 0.34).
Individuals with subacute concussion exhibited worse self-reported and objective sleep than controls, but showed discrepancy between reported and measured sleep characteristics that correlated with concussion severity at diagnosis. Future assessment of sleep discrepancy may improve understanding of post-concussive sleep disturbance.
与对照组相比，对亚急性脑震荡患者的睡眠感知、客观睡眠和神经精神健康状况进行多维度分析。
31名近期脑震荡患者完成了匹兹堡睡眠质量指数、失眠严重程度指数以及患者报告结局测量信息系统中关于抑郁、焦虑、压力和认知功能的测量。从参与者的健康记录中获取脑震荡症状严重程度评分（运动脑震荡评估工具）。睡眠参数来自使用Emfit QS设备至少7天的监测数据（总睡眠时间[TST]、卧床时间、入睡潜伏期、睡眠效率、睡眠中觉醒时间）。使用参数或非参数独立性检验（α = 0.05）将数据与19名对照组进行比较。Pearson相关性分析和线性混合模型评估了数据模式之间的关系。
与对照组相比，脑震荡患者报告的睡眠质量更差，睡眠效率更低，卧床时间更长，入睡潜伏期更长（P < 0.05）。患者报告结局测量信息系统症状评分在显著或接近显著水平上调节了这些关系。对照组在报告的睡眠和测量的睡眠之间表现出一致性（对于TST：r = 0.52；P = 0.023），并且睡眠不满意与睡眠中觉醒之间存在正相关关系（P < 0.05）。在脑震荡患者中未观察到这些关系。此外，报告的睡眠与测量的睡眠之间差异较大的个体在运动脑震荡评估工具脑震荡症状清单上得分更高（β = 9.5/h；P = 0.007；P = 0.022；总体R² = 0.34）。
亚急性脑震荡患者的自我报告睡眠和客观睡眠比对照组更差，但在报告的睡眠特征和测量的睡眠特征之间存在差异，且这种差异与诊断时的脑震荡严重程度相关。未来对睡眠差异的评估可能会增进对脑震荡后睡眠障碍的理解。
