Mangan Aedan, Kim Sukjun, Jones Noah, Brandel Michael G, Heit Jeremy J, Norbash Alexander, Hwang John T, Hawkes Elliot, Morimoto Tania K
Department of Mechanical and Aerospace Engineering, University of California San Diego, San Diego, CA 92093, USA.
Department of Neurosurgery, University of California San Diego, School of Medicine, San Diego, CA 92093, USA.
IEEE Trans Med Robot Bionics. 2025 Aug;7(3):1029-1040. doi: 10.1109/tmrb.2025.3583160. Epub 2025 Jun 25.
Endovascular surgeries generally rely on push-based catheters and guidewires, which require significant training to master and can still result in high stress being exerted on the anatomy, especially in tortuous paths. Because these procedures are so technically challenging to perform, many patients have limited access to high-quality treatment. Although various robotic systems have been developed to enhance navigation capabilities, they can also apply high stresses due to sliding against the vascular walls, impeding movement and raising the risk of vascular damage. Soft growing robots offer a promising alternative since their method of movement via eversion minimizes interaction forces with the environment and enables follow-the-leader navigation through tortuous paths. However, reliable steering of small-scale growing robots remains a significant challenge. We propose a robot architecture that combines a hydraulically-actuated, soft growing robot with a soft, tendon-driven notched continuum robot to overcome the challenges of steering for small-scale growing robots in endovascular procedures. The soft notched continuum robot successfully steers around the most difficult aortic arch type, and a 2.67 mm diameter growing robot-comparable in size to current catheters-deploys from the tip, pulling an aspiration catheter through extremely tortuous vessels. We present the design, manufacturing, and control of the notched continuum robot, growing robot, and proximal actuation subsystem. Overall, this robotic architecture facilitates active steering in proximal anatomy and navigation in tortuous distal vessels, with potential to reduce procedure times and expand access to care.
血管内手术通常依赖于基于推送的导管和导丝,掌握这些技术需要大量的训练,而且仍然可能对解剖结构施加很大的压力,特别是在血管弯曲的路径中。由于这些手术在技术上极具挑战性,许多患者难以获得高质量的治疗。尽管已经开发了各种机器人系统来增强导航能力,但它们在沿血管壁滑动时也会产生很大的压力,阻碍移动并增加血管损伤的风险。柔性生长机器人提供了一种很有前景的替代方案,因为它们通过外翻的运动方式将与环境的相互作用力降至最低,并能够在弯曲路径中实现跟随引导式导航。然而,对小型生长机器人进行可靠的转向控制仍然是一项重大挑战。我们提出了一种机器人架构,将液压驱动的柔性生长机器人与柔性、肌腱驱动的带切口连续体机器人相结合,以克服血管内手术中对小型生长机器人进行转向控制的挑战。柔性带切口连续体机器人成功地绕过了最难处理的主动脉弓类型,并且一个直径为2.67毫米的生长机器人(其尺寸与当前导管相当)从尖端展开,拉动抽吸导管通过极其弯曲的血管。我们介绍了带切口连续体机器人、生长机器人和近端驱动子系统的设计、制造和控制。总体而言,这种机器人架构便于在近端解剖结构中进行主动转向,并在弯曲的远端血管中进行导航,有可能缩短手术时间并扩大治疗的可及性。