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一例以三腔积液为表现的原发性渗出性淋巴瘤罕见诊断:病例报告

A Rare Diagnosis of Primary Effusion Lymphoma Presenting With Three-Cavity Effusion: A Case Report.

作者信息

Movva Hari, Rastgar Yasamin, Obeidat Kinan, Lewis Alexandra

机构信息

Internal Medicine, University of Texas Medical Branch at Galveston, Galveston, USA.

Medical School, University of Texas Medical Branch at Galveston, Galveston, USA.

出版信息

Cureus. 2025 Aug 5;17(8):e89430. doi: 10.7759/cureus.89430. eCollection 2025 Aug.

DOI:10.7759/cureus.89430
PMID:40918767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12410593/
Abstract

We describe a 50-year-old incarcerated transgender female with advanced human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) who was not compliant with antiretroviral therapy (ART). She presented with a three-cavity effusion (peritoneal, pleural, and pericardial) complicated by superimposed spontaneous bacterial peritonitis (SBP). Cytologic smears, flow cytometry, and immunostaining revealed primary effusion lymphoma (PEL). This case report aims to provide a clinical presentation of PEL and offers an overview of its diagnosis and current management strategies.

摘要

我们描述了一名50岁的被监禁的跨性别女性,她患有晚期人类免疫缺陷病毒(HIV)/获得性免疫缺陷综合征(AIDS),且未坚持抗逆转录病毒治疗(ART)。她出现了三腔积液(腹腔、胸腔和心包腔),并并发自发性细菌性腹膜炎(SBP)。细胞学涂片、流式细胞术和免疫染色显示为原发性渗出性淋巴瘤(PEL)。本病例报告旨在提供PEL的临床表现,并概述其诊断和当前的管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8ca/12410593/f95d9df0ffec/cureus-0017-00000089430-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8ca/12410593/176ad562b8c8/cureus-0017-00000089430-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8ca/12410593/f95d9df0ffec/cureus-0017-00000089430-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8ca/12410593/176ad562b8c8/cureus-0017-00000089430-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8ca/12410593/f95d9df0ffec/cureus-0017-00000089430-i02.jpg

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本文引用的文献

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Cureus. 2022 Jun 3;14(6):e25637. doi: 10.7759/cureus.25637. eCollection 2022 Jun.
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Viral, immunologic, and clinical features of primary effusion lymphoma.原发性渗出性淋巴瘤的病毒学、免疫学和临床特征。
Blood. 2019 Apr 18;133(16):1753-1761. doi: 10.1182/blood-2019-01-893339. Epub 2019 Feb 19.
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Current status of treatment for primary effusion lymphoma.原发性渗出性淋巴瘤的治疗现状
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Primary effusion lymphoma involving three body cavities.累及三个体腔的原发性渗出性淋巴瘤。
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Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis.与免疫抑制的移植受者相比,艾滋病毒/艾滋病患者的癌症发病率:一项荟萃分析。
Lancet. 2007 Jul 7;370(9581):59-67. doi: 10.1016/S0140-6736(07)61050-2.
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Primary effusion lymphoma involving both pleural and abdominal cavities in a patient with hepatitis B virus-related liver cirrhosis.一名患有乙型肝炎病毒相关性肝硬化的患者发生了同时累及胸腔和腹腔的原发性渗出性淋巴瘤。
J Formos Med Assoc. 2007 Jun;106(6):504-8. doi: 10.1016/S0929-6646(09)60302-8.
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Clinical features and outcome of primary effusion lymphoma in HIV-infected patients: a single-institution study.HIV感染患者原发性渗出性淋巴瘤的临床特征与转归:一项单机构研究
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The management of ascites in cirrhosis: report on the consensus conference of the International Ascites Club.肝硬化腹水的管理:国际腹水俱乐部共识会议报告
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