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评估小儿推拿联合综合管理对矮小症患儿生长参数及生化指标的影响。

To Evaluate the Effect of Pediatric Massage Combined with Comprehensive Management on Growth Parameters and Biochemical Indicators in Children with Short Stature.

作者信息

Yang Qing, Wu Jing, Deng Xue, Chen Linrui, Chen Yanhui

机构信息

Department of Child Healthcare, Wuhu Hospital of Traditional Chinese Medicine, Wuhu, Anhui Province, 241000, People's Republic of China.

Department of Pediatrics, Fujian Medical University Union Hospital, Fujian, 350000, People's Republic of China.

出版信息

Int J Gen Med. 2025 Aug 31;18:4987-5000. doi: 10.2147/IJGM.S535676. eCollection 2025.

Abstract

PURPOSE

To investigated the effect of pediatric massage combined with comprehensive management on height improvement in children with short stature.

PATIENTS AND METHODS

This retrospective analysis included medical records of 80 children diagnosed with short stature, who received treatment at Wuhu Hospital of Traditional Chinese Medicine between April 2022 and April 2023. According to the recorded treatment modalities, patients were divided into two groups: the control group received standard comprehensive management (including psychological health guidance, diet, sleep, exercise), while the massage group received additional pediatric syndrome-based massage therapy alongside comprehensive treatment. Relevant clinical indicators-including height, weight, BMI (body mass index), IGF-1 (insulin-like growth factor-1), BA (bone age), 25(OH)D (25-hydroxyvitamin D), annual growth velocity (GV), TCM (Traditional Chinese Medicine) symptom scores, as well as cortisol, luteinizing hormone (LH), and growth hormone (GH) levels-were extracted from the medical records and compared between the two groups at baseline and after the recorded treatment period.

RESULTS

When comparing both groups of patients before and after the intervention, significant improvements were observed in height, weight, IGF-1, bone age index (BAI), 25(OH)D levels, GV, and TCM symptom scores (P < 0.05). Notably, the massage group showed significantly greater improvements in height, weight, BAI, IGF-1, and GV compared to the control group (P < 0.05). Furthermore, massage therapy was associated with a reduction in serum cortisol levels and an increase in LH and GH levels, indicating potential endocrine benefits.

CONCLUSION

Pediatric massage combined with comprehensive management effectively promotes improvements in height, weight, and annual growth velocity (GV) among children with short stature.

摘要

目的

探讨小儿推拿联合综合管理对矮小症患儿身高增长的影响。

患者与方法

本回顾性分析纳入了2022年4月至2023年4月在芜湖市中医医院接受治疗的80例矮小症患儿的病历。根据记录的治疗方式,将患者分为两组:对照组接受标准综合管理(包括心理健康指导、饮食、睡眠、运动),而推拿组在综合治疗的基础上还接受了基于小儿综合征的推拿治疗。从病历中提取相关临床指标,包括身高、体重、BMI(体重指数)、IGF-1(胰岛素样生长因子-1)、骨龄(BA)、25(OH)D(25-羟维生素D)、年生长速率(GV)、中医症状评分,以及皮质醇、黄体生成素(LH)和生长激素(GH)水平,并在基线和记录的治疗期后对两组进行比较。

结果

比较两组患者干预前后的情况,发现身高、体重、IGF-1、骨龄指数(BAI)、25(OH)D水平、GV和中医症状评分均有显著改善(P< 0.05)。值得注意的是,推拿组在身高、体重、BAI、IGF-1和GV方面的改善明显大于对照组(P<0.05)。此外,推拿治疗与血清皮质醇水平降低以及LH和GH水平升高有关,表明可能对内分泌有好处。

结论

小儿推拿联合综合管理可有效促进矮小症患儿身高、体重和年生长速率(GV)的改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e4c/12410388/83b6af47828a/IJGM-18-4987-g0001.jpg

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