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规范高危婴儿早期脑瘫检测:通过质量改进举措降低诊断年龄。

Standardizing early cerebral palsy detection in high-risk infants: reducing age at diagnosis through a quality improvement initiative.

作者信息

Ryder Sylvan, Kerner-Rossi Mallory, Brachio Sandhya, Yoon Lisa, Brennan Kathleen, Hammond Jennifer, Paskin Gabriella, Zygmunt Annette, Abreu Anketil, O'Neill Shelagh, Ryan Patricia, Wagner Joan, Penn Anna, Kim Faith

机构信息

Columbia University Medical Center, New York, NY, USA.

NewYork Presbyterian Morgan Stanley Children's Hospital, New York, NY, USA.

出版信息

J Perinatol. 2025 Sep 9. doi: 10.1038/s41372-025-02412-z.

DOI:10.1038/s41372-025-02412-z
PMID:40925942
Abstract

OBJECTIVE

To screen high-risk infants for CP in a level IV NICU and high-risk infant follow-up (HRIF) clinic.

STUDY DESIGN

By using quality improvement methodology, we implemented the General Movement Assessment (GMA) and Hammersmith Infant Neurological Examination (HINE) to screen for CP and lower age at diagnosis. Main balancing measures included no-show rates.

RESULTS

Within the first year, 89% of infants had a GMA in the NICU, 100% in HRIF and 87% had a HINE in HRIF. Median age at diagnosis decreased from 18.5 months adjusted [16.7,19.4] in 2021 to 7.5 months [5.9,14.4; p = 0.01] in 2022 and 8.9 months [6.6,12.2; p = 0.01] in 2023. No-show rates increased in 2022 compared to 2021 (24% vs 17%, p = 0.02).

CONCLUSIONS

By implementing and continuously improving a standard process in the NICU and HRIF, we demonstrated a successful increase in screening for CP leading to a lower age at diagnosis sustained for two years.

摘要

目的

在四级新生儿重症监护病房(NICU)和高危婴儿随访(HRIF)诊所中筛查脑瘫高危婴儿。

研究设计

通过运用质量改进方法,我们实施了全身运动评估(GMA)和哈默史密斯婴儿神经学检查(HINE),以筛查脑瘫并降低诊断年龄。主要平衡指标包括失访率。

结果

在第一年,89%的婴儿在NICU接受了GMA评估,在HRIF中这一比例为100%,87%的婴儿在HRIF接受了HINE评估。诊断时的中位年龄从2021年调整后的18.5个月[16.7,19.4]降至2022年的7.5个月[5.9,14.4;p = 0.01]以及2023年的8.9个月[6.6,12.2;p = 0.01]。与2021年相比,2022年的失访率有所上升(24%对17%,p = 0.02)。

结论

通过在NICU和HRIF中实施并持续改进标准流程,我们成功提高了脑瘫筛查率,使诊断年龄降低并持续了两年。

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J Perinatol. 2025 Sep 9. doi: 10.1038/s41372-025-02412-z.
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本文引用的文献

1
Caregiver Perceptions of Communication About Early Cerebral Palsy or High-Risk Designation in Infants.照顾者对婴儿早期脑瘫或高危状况相关沟通的认知
JAMA Netw Open. 2025 Jul 1;8(7):e2519421. doi: 10.1001/jamanetworkopen.2025.19421.
2
The role of QI collaboratives in neonatology.质量改进协作组在新生儿学中的作用。
J Perinatol. 2025 Apr;45(4):417-425. doi: 10.1038/s41372-024-02124-w. Epub 2024 Oct 9.
3
Early Neurodevelopmental Assessments for Predicting Long-Term Outcomes in Infants at High Risk of Cerebral Palsy.早期神经发育评估预测脑瘫高危婴儿的长期预后。
JAMA Netw Open. 2024 May 1;7(5):e2413550. doi: 10.1001/jamanetworkopen.2024.13550.
4
Exome sequencing reveals genetic heterogeneity and clinically actionable findings in children with cerebral palsy.外显子组测序揭示了脑瘫患儿的遗传异质性和临床可操作的发现。
Nat Med. 2024 May;30(5):1395-1405. doi: 10.1038/s41591-024-02912-z. Epub 2024 May 1.
5
Increasing Prevalence of Cerebral Palsy Among Two-Year-Old Children Born at <27 Weeks of Gestation: A Cohort Study.27 周以下胎龄出生的两岁儿童脑瘫发病率上升:一项队列研究。
J Pediatr. 2024 May;268:113944. doi: 10.1016/j.jpeds.2024.113944. Epub 2024 Feb 8.
6
A Call for Early Detection of Cerebral Palsy.呼吁早期发现脑瘫。
Neoreviews. 2024 Jan 1;25(1):e1-e11. doi: 10.1542/neo.25-1-e1.
7
Automating General Movements Assessment with quantitative deep learning to facilitate early screening of cerebral palsy.利用定量深度学习实现一般性运动评估自动化,以促进脑瘫的早期筛查。
Nat Commun. 2023 Dec 14;14(1):8294. doi: 10.1038/s41467-023-44141-x.
8
Prechtl's General Movements Assessment at writhing age guides MRI use in clinical implementation network.扭动期的普雷茨尔全身运动评估指导临床实施网络中磁共振成像的应用。
Pediatr Res. 2024 Apr;95(5):1188-1190. doi: 10.1038/s41390-023-02856-z. Epub 2023 Nov 2.
9
Redefining cerebral palsies as a diverse group of neurodevelopmental disorders with genetic aetiology.将脑瘫重新定义为一组具有遗传病因的神经发育障碍。
Nat Rev Neurol. 2023 Sep;19(9):542-555. doi: 10.1038/s41582-023-00847-6. Epub 2023 Aug 3.
10
Diagnostic Yield of Exome Sequencing in Cerebral Palsy and Implications for Genetic Testing Guidelines: A Systematic Review and Meta-analysis.脑性瘫痪外显子组测序的诊断率及其对遗传检测指南的影响:系统评价和荟萃分析。
JAMA Pediatr. 2023 May 1;177(5):472-478. doi: 10.1001/jamapediatrics.2023.0008.