Khoudphaithoune Thepsavanh, Lanh Do Thi Kim, Thanh Nguyen Van, Dung Bui Van, Sukon Peerapol, Nam Nguyen Hoai
Department of Animal Surgery and Theriogenology, Faculty of Veterinary Medicine, Vietnam National University of Agriculture, Hanoi, 100000, Vietnam.
Department of Anatomy, Faculty of Veterinary Medicine, Khon Kaen University, Thailand. 123 Moo 16 Mittraphap Rd., Nai-Muang, Muang District, Khon Kaen, 40002, Thailand.
Vet World. 2025 Jul;18(7):2087-2094. doi: 10.14202/vetworld.2025.2087-2094. Epub 2025 Jul 30.
Low birth weight and within-litter variations are major challenges in swine production, often exacerbated by highly prolific sow lines. Nutritional interventions such as amino acid and probiotic supplementation have shown promise, but their combined effects remain unexplored. This study aimed to evaluate the individual and interactive effects of QST 713 and L-arginine supplementation during late gestation on reproductive performance in sows.
A randomized trial was conducted on 247 Landrace × Yorkshire sows allocated to four dietary groups from day 85 of gestation to farrowing: (1) Basal diet (control), (2) basal diet + , (3) basal diet + L-arginine, and (4) basal diet + both supplements. Reproductive outcomes-including individual birth weight (IBW), total litter birth weight (TBW), born-alive birth weight (NBABW), proportion of runt (<1.1 kg) and large piglets (>1.5 kg), and within-litter coefficient of variation in birth weight [CVBW])-were assessed. Linear and generalized linear mixed models were used for analysis.
Co-supplementation with and L-arginine significantly increased IBW (1434.7 g vs. 1310.0 g, p < 0.001), TBW (19.6 kg vs. 16.9 kg, p < 0.001), NBABW (18.1 kg vs. 15.9 kg, p = 0.006), and the proportion of large piglets (33.7% vs. 19.5%, p = 0.0002), while reducing runt piglet incidence (4.0% vs. 14.4%, p < 0.001). Neither supplement alone produced significant improvements. No treatment significantly affected litter size, CVBW, stillbirth, or mummification rates.
Co-supplementation of sows with and L-arginine during late gestation produces synergistic impro-vements in piglet birth weight and litter quality. This strategy offers a practical and cost-effective approach to enhance swine reproductive efficiency.
低出生体重和窝内差异是养猪生产中的主要挑战，高产母猪品系往往会加剧这些问题。氨基酸和益生菌补充等营养干预措施已显示出一定前景，但其联合效果仍未得到探索。本研究旨在评估妊娠后期补充QST 713和L-精氨酸对母猪繁殖性能的个体和交互作用。
对247头长白×大白母猪进行随机试验，从妊娠第85天至分娩将其分为四个日粮组：(1)基础日粮（对照组），(2)基础日粮+ ，(3)基础日粮+L-精氨酸，(4)基础日粮+两种补充剂。评估繁殖结果，包括个体出生体重（IBW）、总窝出生体重（TBW）、活产出生体重（NBABW）、弱小仔猪（<1.1千克）和大仔猪（>1.5千克）的比例以及窝内出生体重变异系数[CVBW]）。采用线性和广义线性混合模型进行分析。
同时补充 和L-精氨酸显著提高了IBW（1434.7克对1310.0克，p<0.001）、TBW（19.6千克对16.9千克，p<0.001）、NBABW（18.1千克对15.9千克，p = 0.006）和大仔猪比例（33.7%对19.5%，p = 0.0002），同时降低了弱小仔猪发生率（4.0%对14.4%，p<0.001）。单独使用任何一种补充剂均未产生显著改善。没有处理显著影响产仔数、CVBW、死产或木乃伊化率。
妊娠后期母猪同时补充 和L-精氨酸可协同提高仔猪出生体重和窝质量。该策略为提高猪繁殖效率提供了一种实用且经济有效的方法。
