Aboussabr Meryem, Oueriagli Salah Nabih, Zahfir Ikram, Benameur Yassir, Sahel Omar Ait, Doudouh Abderrahim
Department of Nuclear Medicine, Mohammed V Military Teaching Hospital, Rabat, Morocco.
Indian J Nucl Med. 2025 May-Jun;40(3):156-160. doi: 10.4103/ijnm.ijnm_18_25. Epub 2025 Aug 7.
Thyroglossal duct carcinoma is a rare clinical condition, accounting for only 1% of operated cases. It is characterized by ectopic thyroid adenocarcinoma developing within thyroglossal duct cysts (TGDCs). Among these, papillary thyroid carcinoma is the most frequently reported pathological type. The clinical presentation of thyroglossal duct malignancies is often nonspecific, with diagnosis typically confirmed postoperatively via the Sistrunk procedure. Due to the rarity of these cases and their generally favorable prognosis, standardized diagnostic and treatment guidelines have not yet been established. We report a rare case of a 31-year-old patient who underwent surgery for an anterior neck mass that had developed over the years. Histopathological examination revealed a Hürthle cell carcinoma occurring in a thyroglossal duct remnant. Following this diagnosis, the patient underwent a total thyroidectomy. The postoperative management plan included radioactive iodine therapy and thyroid hormone suppressive therapy.
甲状舌管癌是一种罕见的临床病症，仅占手术病例的1%。其特征是在甲状舌管囊肿（TGDCs）内发生异位甲状腺腺癌。其中，乳头状甲状腺癌是最常报道的病理类型。甲状舌管恶性肿瘤的临床表现通常不具有特异性，诊断通常在术后通过Sistrunk手术得以证实。由于这些病例罕见且总体预后良好，尚未建立标准化的诊断和治疗指南。我们报告一例罕见病例，一名31岁患者因多年来颈部前方出现肿物而接受手术。组织病理学检查显示在甲状舌管残余组织中发生了许特莱细胞癌。确诊后，该患者接受了全甲状腺切除术。术后管理计划包括放射性碘治疗和甲状腺激素抑制治疗。
