Giorgino Francesco, Alzaid Fawaz, Pantea Stoian Anca, Chan Juliana C N, Ji Linong, Lumu William, Manrique Helard, Mauricio Didac, Saboo Banshi, Senior Peter A, Yabe Daisuke, Zoungas Sophia, Meireles Manuela, Mathieu Chantal, Czupryniak Leszek
Department of Precision and Regenerative Medicine and Ionian Area, Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy.
Dasman Diabetes Institute, Kuwait City, Kuwait.
Diabetologia. 2025 Sep 10. doi: 10.1007/s00125-025-06504-5.
This review article, developed by the EASD Global Council, addresses the growing global challenges in diabetes research and care, highlighting the rising prevalence of diabetes, the increasing complexity of its management and the need for a coordinated international response. With regard to research, disparities in funding and infrastructure between high-income countries and low- and middle-income countries (LMICs) are discussed. The under-representation of LMIC populations in clinical trials, challenges in conducting large-scale research projects, and the ethical and legal complexities of artificial intelligence integration are also considered as specific issues. The development of global research networks and strategies for improved training, standardisation of data and enhanced accessibility to big data analytics to drive innovation and personalised medicine are recommended. With regard to diabetes care, inequalities in access to essential medications, particularly insulin and novel therapies, and disparities in healthcare infrastructure are discussed. Proposed initiatives include international support programmes, improved healthcare provider training and the inclusion of newer diabetes medications in essential drug lists. The importance of global screening programmes, a universal diabetes education curriculum and standardised healthcare checklists is also emphasised. Regarding healthcare organisation, the development of national diabetes registers, benchmarking performance across regions and strengthening international collaborations are highly advised. The role of diabetes specialists as care coordinators and the need for structured assessments to improve early intervention and long-term outcomes are also discussed. Ultimately, the EASD Global Council urges action for a unified, global approach to diabetes research and care to bridge the gap between scientific innovation and clinical practice, ensuring equitable healthcare worldwide.
这篇由欧洲糖尿病研究协会全球委员会撰写的综述文章，探讨了糖尿病研究与护理领域日益严峻的全球挑战，强调了糖尿病患病率的上升、管理复杂性的增加以及采取协调一致的国际应对措施的必要性。在研究方面，讨论了高收入国家与低收入和中等收入国家（LMICs）在资金和基础设施方面的差距。LMICs人群在临床试验中的代表性不足、开展大规模研究项目的挑战以及人工智能整合中的伦理和法律复杂性也被视为具体问题。建议发展全球研究网络以及制定改善培训、数据标准化和增强大数据分析可及性的策略，以推动创新和个性化医疗。在糖尿病护理方面，讨论了获取基本药物（尤其是胰岛素和新型疗法）的不平等现象以及医疗基础设施的差异。提议的举措包括国际支持计划、改善医疗服务提供者培训以及将更新的糖尿病药物纳入基本药物清单。还强调了全球筛查计划、通用糖尿病教育课程和标准化医疗检查表的重要性。在医疗组织方面，强烈建议建立国家糖尿病登记系统、跨地区进行绩效基准评估以及加强国际合作。还讨论了糖尿病专科医生作为护理协调员的作用以及进行结构化评估以改善早期干预和长期结果的必要性。最终，欧洲糖尿病研究协会全球委员会敦促采取行动，以统一的全球方法开展糖尿病研究与护理，弥合科学创新与临床实践之间的差距，确保全球医疗公平。
