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Precision cancer medicine 2025: some concerns.

作者信息

Nygren Peter

机构信息

Department of Immunology, Genetics and Pathology, Rudbecklaboratoriet, Uppsala University, Uppsala, Sweden.

出版信息

Acta Oncol. 2025 Sep 11;64:1202-1204. doi: 10.2340/1651-226X.2025.44604.

DOI:10.2340/1651-226X.2025.44604
PMID:40932007
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12439214/
Abstract
摘要

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本文引用的文献

1
The present and future of precision oncology and tumor-agnostic therapeutic approaches.精准肿瘤学与肿瘤非特异性治疗方法的现状与未来。
Oncologist. 2025 Jun 4;30(6). doi: 10.1093/oncolo/oyaf152.
2
Medical digital twins: enabling precision medicine and medical artificial intelligence.医学数字孪生:推动精准医学与医学人工智能发展
Lancet Digit Health. 2025 Jun 14:100864. doi: 10.1016/j.landig.2025.02.004.
3
Encorafenib, Cetuximab, and mFOLFOX6 in -Mutated Colorectal Cancer.恩考芬尼、西妥昔单抗和改良FOLFOX6方案用于KRAS基因突变型结直肠癌的治疗
N Engl J Med. 2025 Jun 26;392(24):2425-2437. doi: 10.1056/NEJMoa2501912. Epub 2025 May 30.
4
Accelerating precision oncology by converging pragmatic trials and real-world evidence.通过融合实用试验和真实世界证据加速精准肿瘤学发展
Nat Rev Drug Discov. 2025 Mar 13. doi: 10.1038/d41573-025-00047-5.
5
Hallmarks of artificial intelligence contributions to precision oncology.人工智能对精准肿瘤学贡献的标志。
Nat Cancer. 2025 Mar;6(3):417-431. doi: 10.1038/s43018-025-00917-2. Epub 2025 Mar 7.
6
Ethical and Clinical Considerations in Ordering and Responding to Molecular Diagnostics and Circulating Tumor DNA as the Science Evolves.随着科学的发展,在订购和回应分子诊断及循环肿瘤DNA方面的伦理与临床考量
JCO Oncol Pract. 2024 Nov;20(11):1508-1514. doi: 10.1200/OP-24-00481. Epub 2024 Nov 12.
7
The ESMO Tumour-Agnostic Classifier and Screener (ETAC-S): a tool for assessing tumour-agnostic potential of molecularly guided therapies and for steering drug development.ESMO 肿瘤不可知分类器和筛查器(ETAC-S):一种用于评估基于分子靶向治疗的肿瘤不可知性和指导药物开发的工具。
Ann Oncol. 2024 Nov;35(11):936-953. doi: 10.1016/j.annonc.2024.07.730. Epub 2024 Aug 25.
8
PCM4EU and PRIME-ROSE: Collaboration for implementation of precision cancer medicine in Europe.PCM4EU 和 PRIME-ROSE:在欧洲实施精准肿瘤医学的合作。
Acta Oncol. 2024 May 23;63:385-391. doi: 10.2340/1651-226X.2024.34791.
9
Cancer biomarkers: Emerging trends and clinical implications for personalized treatment.癌症生物标志物:个性化治疗的新兴趋势和临床意义。
Cell. 2024 Mar 28;187(7):1617-1635. doi: 10.1016/j.cell.2024.02.041.
10
A federated learning system for precision oncology in Europe: DigiONE.欧洲用于精准肿瘤学的联邦学习系统:DigiONE。
Nat Med. 2024 Feb;30(2):334-337. doi: 10.1038/s41591-023-02715-8.