Fighting the flu in the tropics: The role of influenza vaccination in Southeast Asia.

Influenza remains a significant public health concern globally, including in Southeast Asia, where unique epidemiological patterns and year-round virus circulation necessitate tailored vaccination strategies. This article briefly explores the historical milestones of influenza vaccine development, tracing its evolution from early inactivated vaccines to modern formulations. It also examines the annual inclusion of specific virus strains in vaccines, detailing the codename system for strain identification. In tropical regions like Southeast Asia, the need for influenza vaccination is debated due to continuous exposure; however, evidence supports its efficacy in reducing disease burden. It also discusses World Health Organization guidelines for optimal vaccination timing based on regional influenza activity and identifies target populations, including high-risk groups, and considerations for broader immunization efforts. Addressing these factors can enhance vaccination strategies and reduce influenza's impact in Southeast Asia.