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双侧动眼神经麻痹:急性基底动脉闭塞桥接溶栓的一种罕见并发症。

Bilateral Oculomotor Nerve Palsy: A Rare Complication of Bridging Thrombolysis for Acute Basilar Artery Occlusion.

作者信息

Lv Shuangyun, Liu Ronghui, Sun Jiapeng, Liu Hongmei, Guo Xin, Ding Changxia

机构信息

Department of Neurology, Huanghua Municipal People's Hospital, Huanghua, Hebei, 061100, People's Republic of China.

Department of Neurology, the First Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People's Republic of China.

出版信息

Int Med Case Rep J. 2025 Sep 4;18:1141-1146. doi: 10.2147/IMCRJ.S532206. eCollection 2025.

Abstract

Acute vertebrobasilar artery occlusion (AVBAO) accounts for only 1-2% of ischemic stroke, but it has high disability and mortality rates. Mechanical thrombectomy (MT) combined with intravenous thrombolysis can quickly achieve vascular recanalization and significantly improve patient prognosis. This report describes a 73-year-old male who was admitted to the hospital in a coma due to AVBAO. After MT, successful recanalization of the basilar artery was achieved; however, the patient subsequently developed the rare but serious complication of bilateral oculomotor nerve palsy. The report emphasizes the need for careful preoperative planning, including detailed assessment of vascular anatomy and thrombus characteristics, and the importance of operator expertise. Improved intraoperative technique and close postoperative monitoring may help prevent complications such as vessel injury or embolic recurrence. Additionally, clinicians should be aware of the limitations of early DWI (Diffusion-weighted imaging) in detecting brainstem infarcts and of the need for clinical vigilance in the postoperative period.

摘要

急性椎基底动脉闭塞(AVBAO)仅占缺血性卒中的1%-2%,但其致残率和死亡率很高。机械取栓术(MT)联合静脉溶栓可迅速实现血管再通,并显著改善患者预后。本报告描述了一名73岁男性,因AVBAO昏迷入院。MT术后,基底动脉成功再通;然而,患者随后出现了罕见但严重的双侧动眼神经麻痹并发症。该报告强调了术前仔细规划的必要性,包括对血管解剖结构和血栓特征的详细评估,以及术者专业知识的重要性。改进术中技术和术后密切监测可能有助于预防血管损伤或栓塞复发等并发症。此外,临床医生应意识到早期弥散加权成像(DWI)在检测脑干梗死方面的局限性,以及术后临床警惕的必要性。

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