Liu Yifan, He Junzhe, Lyu Donghao, Yang Xinyue, Zhang Haoyu, Tu Siqi, Yao Yuntao, Wei Maodong, Li Yuanan, Zhao Zihui, Huang Runzhi, Lu Bingnan, Xu Xiao, Pan Xiuwu
Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Front Oncol. 2025 Aug 26;15:1537805. doi: 10.3389/fonc.2025.1537805. eCollection 2025.
The vital role metabolism plays in RCC, a global disease with huge disease burden, has been widely acknowledged. However, bibliometric analysis remains underexplored in the context of metabolism in RCC.
The Web of Science database was adopted to obtain relevant publications for further bibliometric analysis of countries, institutions, authors, journals, publications, references and keywords. Literature reading and keyword co-occurrence analysis were employed to figure out major points and hotspots in this field. The analysis was conducted by biblioshiny based on Bibliometrix package in R version 4.3.2.
From 15 May 2015 to 15 May 2025, 3010 relevant publications were retrieved. China was the most productive country and USA was the country with the highest total citations. The most productive institution was "Harvard University". WANG Y published 46 publications with an H-index of 16. Core journals were identified with Bradford's law. Additionally, three major points and hotspots were identified and discussed through bibliometric analysis and targeted literature reading.
Our research provided a reference for future basic and clinical research through summarizing past research findings, analyzing current research hotspots, and prospecting the future development of research. "Metabolic alterations in RCC", "Metabolic syndrome and RCC", "Microbiome and RCC" were major points and hot spots in this field. In the future, a broader metabolic map could be made and more researches concerning metabolism during RCC treatment and drug resistance might bring more clinical significance.
代谢在肾癌（一种具有巨大疾病负担的全球性疾病）中所起的重要作用已得到广泛认可。然而，在肾癌代谢领域，文献计量分析仍未得到充分探索。
采用科学网数据库获取相关出版物，以对国家、机构、作者、期刊、出版物、参考文献和关键词进行进一步的文献计量分析。运用文献阅读和关键词共现分析来找出该领域的要点和热点。分析由biblioshiny基于R版本4.3.2中的Bibliometrix包进行。
从2015年5月15日至2025年5月15日，共检索到3010篇相关出版物。中国是发文量最多的国家，美国是总被引次数最高的国家。发文量最多的机构是“哈佛大学”。王Y发表了46篇出版物，H指数为16。利用布拉德福德定律确定了核心期刊。此外，通过文献计量分析和有针对性的文献阅读，确定并讨论了三个要点和热点。
我们的研究通过总结过去的研究成果、分析当前的研究热点以及展望未来研究的发展，为未来的基础和临床研究提供了参考。“肾癌的代谢改变”、“代谢综合征与肾癌”、“微生物群与肾癌”是该领域的要点和热点。未来，可以绘制更广泛的代谢图谱，并开展更多关于肾癌治疗和耐药过程中代谢的研究可能会带来更多临床意义。
