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心脏手术中腹内高压的危险因素:一项系统评价和荟萃分析。

Risk factors of intraabdominal hypertension in cardiac surgery: A systematic review and meta-analysis.

作者信息

Öztürk Selen, Tekin Gözde, Uzandı Hüseyin, Kızılay Mehmet, Öztürk İbrahim

机构信息

Department of Cardiovascular Surgery, Health Sciences University, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Türkiye.

Department of Anesthesiology and Reanimation, Göztepe Prof. Süleyman Yalçın City Hospital, İstanbul, Türkiye.

出版信息

Turk Gogus Kalp Damar Cerrahisi Derg. 2025 Jul 21;33(3):321-328. doi: 10.5606/tgkdc.dergisi.2025.27656. eCollection 2025 Jul.

DOI:10.5606/tgkdc.dergisi.2025.27656
PMID:40936981
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12421560/
Abstract

BACKGROUND

In this review, we discuss the risk factors of intraabdominal hypertension developing after cardiac surgery.

METHODS

We used records from electronic databases (PubMed, Scopus, Web of Science and Ovid) between 1980 and 2025. All studies in which possible pre- and intraoperative risk factors (age, sex, hypertension, diabetes mellitus, lung disease, coronary artery bypass grafting, body mass index and, cardiopulmonary bypass duration) were recorded were included in the analysis. The results of the studies were evaluated with a random or fixed effect model depending on the presence of heterogeneity ( >25%).

RESULTS

A total of 4,286 articles were found from the database search. After analyzing the abstract and full texts, six articles which met the inclusion criteria and covered 696 patients were included in the analysis. The overall rate of intraabdominal hypertension was 44.68%. Age (standardized mean difference [SMD]: 0.303, 95% confidence interval [CI]: 0.123-0.484, p<0.001), hypertension (odds ratio [OR]=0.524, 95% CI: 0.087-0.960, p=0.019), body mass index (SMD: 0.532, 95% CI: 0.004-1.061, p=0.048), and cardiopulmonary bypass duration (SMD: 0.545, 95% CI: 0.184-0.907, p=0.003) were preoperative risk factors.

CONCLUSION

The patient's age, hypertension, body mass index, and duration of cardiopulmonary bypass are the risk factors for the development of intraabdominal hypertension after cardiac surgery. However, larger studies are needed to avoid heterogeneity of results.

摘要

背景

在本综述中,我们讨论心脏手术后发生腹腔内高压的危险因素。

方法

我们使用了1980年至2025年电子数据库(PubMed、Scopus、Web of Science和Ovid)中的记录。分析纳入所有记录了可能的术前和术中危险因素(年龄、性别、高血压、糖尿病、肺部疾病、冠状动脉搭桥术、体重指数和体外循环持续时间)的研究。根据异质性(>25%)的存在情况,使用随机或固定效应模型评估研究结果。

结果

通过数据库检索共找到4286篇文章。在分析摘要和全文后,纳入了6篇符合纳入标准且涵盖696例患者的文章进行分析。腹腔内高压的总体发生率为44.68%。年龄(标准化均数差[SMD]:0.303,95%置信区间[CI]:0.123 - 0.484,p<0.001)、高血压(比值比[OR]=0.524,95% CI:0.087 - 0.960,p=0.019)、体重指数(SMD:0.532,95% CI:0.004 - 1.061,p=0.048)和体外循环持续时间(SMD:0.545,95% CI:0.184 - 0.907,p=0.003)是术前危险因素。

结论

患者的年龄、高血压、体重指数和体外循环持续时间是心脏手术后发生腹腔内高压的危险因素。然而,需要更大规模的研究以避免结果的异质性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91f9/12421560/f45fd8319c0e/TJTCS-2025-33-3-321-328-F5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91f9/12421560/82fb246822da/TJTCS-2025-33-3-321-328-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91f9/12421560/42256be48f42/TJTCS-2025-33-3-321-328-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91f9/12421560/a7827d0a4adb/TJTCS-2025-33-3-321-328-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91f9/12421560/93dff0bd4978/TJTCS-2025-33-3-321-328-F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91f9/12421560/f45fd8319c0e/TJTCS-2025-33-3-321-328-F5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91f9/12421560/82fb246822da/TJTCS-2025-33-3-321-328-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91f9/12421560/42256be48f42/TJTCS-2025-33-3-321-328-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91f9/12421560/a7827d0a4adb/TJTCS-2025-33-3-321-328-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91f9/12421560/93dff0bd4978/TJTCS-2025-33-3-321-328-F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91f9/12421560/f45fd8319c0e/TJTCS-2025-33-3-321-328-F5.jpg

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本文引用的文献

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Interdiscip Cardiovasc Thorac Surg. 2024 Feb 2;38(2). doi: 10.1093/icvts/ivae019.
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Turk Gogus Kalp Damar Cerrahisi Derg. 2020 Jan 23;28(1):134-142. doi: 10.5606/tgkdc.dergisi.2020.18662. eCollection 2020 Jan.
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