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Nitride-Silver Hybrid PCF-SPR Biosensor: A High-Sensitivity Platform for Synchronous Monitoring of Low-Concentration Analytes and Temperature.

作者信息

Liang Chenyu, Wang Junzhu, Zhu Jiaxuan, Zhao Jie, Zhang Kai

机构信息

College of Metrology Measurement and Instrument, China Jiliang University, Hangzhou 310018, China.

出版信息

Sensors (Basel). 2025 Aug 26;25(17):5292. doi: 10.3390/s25175292.

DOI:10.3390/s25175292
PMID:40942722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12431535/
Abstract

This study proposes a dual-parameter photonic crystal fiber-based surface plasmon resonance (SPR) sensor for simultaneous refractive index and temperature detection. The sensor architecture incorporates an asymmetric air hole lattice, featuring elliptical inner holes (aspect ratio: 1.5) to enhance birefringence and axially aligned outer circular holes to optimize surface plasmon coupling. Horizontally, symmetrically deposited silver films and silicon nitride layers constitute the RI-sensing channel, while a vertically machined PDMS-coated silver-nitride structure enables temperature responsivity. The temperature-sensing channel delivers a sensitivity of 20 nm/°C within 0-100 °C, while the RI channel achieves a peak sensitivity of 18,600 nm/RIU across = 1.33-1.41 with a resolution of 5.38 × 10 RIU. Notably, cross-sensitivity between the two channels remains below 5%, underscoring the sensor's capability for independent dual-parameter analysis. This low-interference, high-sensitivity platform holds significant promise for advanced biosensing applications requiring real-time multiparametric monitoring.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dfd/12431535/0e479d358c1a/sensors-25-05292-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dfd/12431535/0e479d358c1a/sensors-25-05292-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dfd/12431535/0e479d358c1a/sensors-25-05292-g009.jpg

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本文引用的文献

1
Photonic crystal fiber sensors in the THz domain: A leap forward in alcohol detection.太赫兹波段的光子晶体光纤传感器:酒精检测的一大飞跃。
Heliyon. 2024 Dec 6;10(24):e40945. doi: 10.1016/j.heliyon.2024.e40945. eCollection 2024 Dec 30.
2
A PCF Sensor Design Using Biocompatible PDMS for Biosensing.一种使用生物相容性聚二甲基硅氧烷(PDMS)进行生物传感的光子晶体光纤(PCF)传感器设计。
Polymers (Basel). 2024 Apr 10;16(8):1042. doi: 10.3390/polym16081042.
3
Surface plasmon resonance biosensor based on gold-coated side-polished hexagonal structure photonic crystal fiber.
基于镀金黄侧面抛光六角结构光子晶体光纤的表面等离子体共振生物传感器。
Opt Express. 2017 Aug 21;25(17):20313-20322. doi: 10.1364/OE.25.020313.
4
Amplifying the signal of localized surface plasmon resonance sensing for the sensitive detection of Escherichia coli O157:H7.放大局域表面等离子体共振传感信号用于灵敏检测大肠杆菌 O157:H7。
Sci Rep. 2017 Jun 12;7(1):3288. doi: 10.1038/s41598-017-03495-1.
5
Surface plasmon resonance sensor based on polymer photonic crystal fibers with metal nanolayers.基于金属纳米层的聚合物光子晶体光纤的表面等离子体共振传感器。
Sensors (Basel). 2013 Jan 15;13(1):956-65. doi: 10.3390/s130100956.