• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

特刊“营养与健康中的色氨酸3.0”

Special Issue "Tryptophan in Nutrition and Health 3.0".

作者信息

Poeggeler Burkhard, Singh Sandeep Kumar, Sambamurti Kumar, Pappolla Miguel A

机构信息

Department of Physiology, Johann-Friedrich-Blumenbach Institute for Zoology and Anthropology, Faculty of Biology and Psychology, Georg August University Göttingen, Zappenburg 2, D-38524 Sassenburg, Germany.

Department of Medical Biotechnology, All India Institute of Medical Sciences (AIIMS) Nagpur, Nagpur 441108, Maharashtra, India.

出版信息

Int J Mol Sci. 2025 Aug 30;26(17):8443. doi: 10.3390/ijms26178443.

DOI:10.3390/ijms26178443
PMID:40943365
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12428979/
Abstract

Tryptophan is the rate-limiting essential amino acid and thus a building block of life that is needed for protein synthesis [...].

摘要

色氨酸是限速必需氨基酸,因此是蛋白质合成所需的生命组成部分[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b42/12428979/bf4118e3a402/ijms-26-08443-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b42/12428979/bf4118e3a402/ijms-26-08443-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b42/12428979/bf4118e3a402/ijms-26-08443-g001.jpg

相似文献

1
Special Issue "Tryptophan in Nutrition and Health 3.0".特刊“营养与健康中的色氨酸3.0”
Int J Mol Sci. 2025 Aug 30;26(17):8443. doi: 10.3390/ijms26178443.
2
Amino acid transporter LAT1 (SLC7A5) promotes metabolic rewiring in TNBC progression through the L-Trp/QPRT/NAD pathway.氨基酸转运体LAT1(SLC7A5)通过L-色氨酸/QPRT/烟酰胺腺嘌呤二核苷酸途径促进三阴性乳腺癌进展中的代谢重塑。
J Exp Clin Cancer Res. 2025 Jul 3;44(1):190. doi: 10.1186/s13046-025-03446-z.
3
Differing planes of nutrition alter serum and histotroph amino acid composition in nonpregnant, multiparous beef cows on day 3 of the estrous cycle.不同营养水平会改变发情周期第 3 天非妊娠、多胎次肉牛的血清和组织液氨基酸组成。
J Anim Sci. 2024 Jan 3;102. doi: 10.1093/jas/skae199.
4
Avoidance of the use of tryptophan in buried chromosomal proteins as a mechanism for reducing photo/oxidative damage to genomes.避免在埋藏的染色体蛋白中使用色氨酸作为减少基因组光/氧化损伤的一种机制。
J Photochem Photobiol B. 2023 Aug;245:112733. doi: 10.1016/j.jphotobiol.2023.112733. Epub 2023 Jun 1.
5
Sex Differences in Tryptophan Metabolism: A Systematic Review Focused on Neuropsychiatric Disorders.色氨酸代谢的性别差异:侧重于神经精神疾病的系统评价。
Int J Mol Sci. 2023 Mar 22;24(6):6010. doi: 10.3390/ijms24066010.
6
The Fate of Dietary Tryptophan in Fish: Unveiling Its Sources, Transport, Metabolism, and Multifaceted Impacts.鱼类膳食色氨酸的命运:揭示其来源、转运、代谢及多方面影响
J Nutr. 2025 Jul;155(7):2017-2042. doi: 10.1016/j.tjnut.2025.05.034. Epub 2025 May 24.
7
Effects of Different Protein Sources on Amino Acid Absorption and Plasma Appearance of Tryptophan, Large Neutral Amino Acids, and Tryptophan Metabolites in Pigs.不同蛋白质源对猪氨基酸吸收和色氨酸、大中性氨基酸及色氨酸代谢产物血浆出现的影响。
J Nutr. 2024 Oct;154(10):2948-2962. doi: 10.1016/j.tjnut.2024.07.010. Epub 2024 Jul 15.
8
Tryptophan metabolism as a 'reflex' feature of neuroimmune communication: Sensor and effector functions for the indoleamine-2, 3-dioxygenase kynurenine pathway.色氨酸代谢作为神经免疫通讯的“反射”特征:吲哚胺 2,3-双加氧酶犬尿氨酸途径的传感器和效应器功能。
J Neurochem. 2024 Sep;168(9):3333-3357. doi: 10.1111/jnc.16015. Epub 2023 Dec 16.
9
Tryptophanase Expressed by Halts Breast Cancer Cell Growth In Vitro and Inhibits Production of Immunosuppressive Kynurenine.由[具体内容缺失]表达的色氨酸酶在体外可抑制乳腺癌细胞生长并抑制免疫抑制性犬尿氨酸的产生。
Microorganisms. 2023 May 22;11(5):1355. doi: 10.3390/microorganisms11051355.
10
Gut microbiota and the tryptophan-kynurenine pathway in anxiety: new insights and treatment strategies.肠道微生物群与焦虑中的色氨酸-犬尿氨酸途径:新见解与治疗策略
J Neural Transm (Vienna). 2025 May 14. doi: 10.1007/s00702-025-02938-8.

引用本文的文献

1
MiR-26b-5p mediates radioresistance and immunosuppression via targeting PRKCD in non-small cell lung cancer.微小RNA-26b-5p通过靶向蛋白激酶Cδ在非小细胞肺癌中介导放射抗性和免疫抑制。
J Cancer Res Clin Oncol. 2025 Sep 18;151(10):262. doi: 10.1007/s00432-025-06310-x.

本文引用的文献

1
Biosynthetic Pathways of Tryptophan Metabolites in Strain: Insights and Implications.色氨酸代谢物生物合成途径在菌株中的研究进展:分析与启示。
Int J Mol Sci. 2024 Apr 26;25(9):4747. doi: 10.3390/ijms25094747.
2
Microbiota, Tryptophan and Aryl Hydrocarbon Receptors as the Target Triad in Parkinson's Disease-A Narrative Review.微生物群、色氨酸和芳烃受体作为帕金森病的目标三联体——一篇叙述性综述
Int J Mol Sci. 2024 Mar 2;25(5):2915. doi: 10.3390/ijms25052915.
3
Effects of Rumen-Protected L-Tryptophan Supplementation on Productivity, Physiological Indicators, Blood Profiles, and Heat Shock Protein Gene Expression in Lactating Holstein Cows under Heat Stress Conditions.
热应激条件下,瘤胃保护性L-色氨酸添加对泌乳荷斯坦奶牛生产性能、生理指标、血液参数及热休克蛋白基因表达的影响
Int J Mol Sci. 2024 Jan 19;25(2):1217. doi: 10.3390/ijms25021217.
4
Tryptophan Metabolism in Postmenopausal Women with Functional Constipation.绝经后功能性便秘妇女的色氨酸代谢。
Int J Mol Sci. 2023 Dec 24;25(1):273. doi: 10.3390/ijms25010273.
5
Dietary Kynurenine Pathway Metabolites-Source, Fate, and Chromatographic Determinations.饮食色氨酸代谢途径代谢产物——来源、命运和色谱测定。
Int J Mol Sci. 2023 Nov 14;24(22):16304. doi: 10.3390/ijms242216304.
6
Tryptophan-Starved Human Cells Overexpressing Tryptophanyl-tRNA Synthetase Enhance High-Affinity Tryptophan Uptake via Enzymatic Production of Tryptophanyl-AMP.色氨酸饥饿的人源细胞过表达色氨酰-tRNA 合成酶通过酶法生成色氨酰-AMP 增强高亲和力色氨酸摄取。
Int J Mol Sci. 2023 Oct 22;24(20):15453. doi: 10.3390/ijms242015453.
7
Tryptophan Modulatory Role in European Seabass () Immune Response to Acute Inflammation under Stressful Conditions.色氨酸对欧洲鲈鱼()在应激条件下急性炎症反应的调节作用。
Int J Mol Sci. 2022 Oct 18;23(20):12475. doi: 10.3390/ijms232012475.