Riccio Paolo, Jirillo Emilio
Independent Researcher, 70126 Bari, Italy.
Interdisciplinary Department of Medicine, Medical School, University of Bari, 70100 Bari, Italy.
Nutrients. 2025 Aug 24;17(17):2740. doi: 10.3390/nu17172740.
: For the first time, humanity is facing the worldwide challenge of global population aging over 80 years. As individuals age, energy acquisition and metabolism undergo significant changes, leading to a progressive decline in energy intake, absorption, and utilization. These changes contribute to malnutrition, loss of muscle mass, frailty, hormonal decline, mineral depletion, and impaired hydration, all of which increase the risk of morbidity and decrease quality of life. In addition, as life expectancy increases, advanced age often brings a gradual loss of autonomy, mirroring early-life dependency. : Addressing this age shift requires targeted interventions to support the wellness of the growing very elderly population. This review provides an overview of healthy aging through an integrated approach that includes nutritional intervention, lifestyle modifications, and targeted supplementation to support functional independence and overall well-being in older adults. The guiding principle is that longevity matters less than aging well.
人类首次面临全球80岁以上人口老龄化这一全球性挑战。随着个体年龄增长,能量获取和新陈代谢会发生显著变化,导致能量摄入、吸收和利用逐渐下降。这些变化会导致营养不良、肌肉量流失、身体虚弱、激素水平下降、矿物质缺乏以及水合作用受损,所有这些都会增加发病风险并降低生活质量。此外,随着预期寿命的增加,高龄往往会带来自主性的逐渐丧失,这与早年的依赖状态相似。应对这一年龄转变需要有针对性的干预措施,以支持日益增多的高龄老人的健康。本综述通过一种综合方法概述了健康老龄化,该方法包括营养干预、生活方式改变以及有针对性的补充,以支持老年人的功能独立性和整体幸福感。指导原则是活得长久不如活得健康。