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65岁及以上老年患者踝关节骨折的管理概述:一项范围综述

An overview on the management of ankle fractures in elderly patients aged 65 and over: a scoping review.

作者信息

Liu Gang, Sun Zhijian, Yang Minghui, Wu Xinbao, Giannoudis Peter V

机构信息

Department of Orthopaedics Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.

Academic Department of Trauma and Orthopaedics, University of Leeds, Leeds, United Kingdom.

出版信息

Eur J Orthop Surg Traumatol. 2025 Sep 13;35(1):396. doi: 10.1007/s00590-025-04512-0.

Abstract

PURPOSE

Ankle fractures are increasingly common in the elderly and present unique challenges due to osteoporosis, comorbidities, and frailty. Management remains controversial, with surgical fixation generally favored, though the optimal approach is debated. This scoping review aimed to map current evidence on the management of ankle fractures in patients aged 65 and over, highlighting treatment strategies, outcomes, and gaps in knowledge.

METHODS

A scoping review was conducted in accordance with The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR). We systematically searched PubMed, Embase, and Cochrane Library from 2010 to 2024. Eligible studies reporting treatment outcomes in elderly patients were included. Data were charted and summarized narratively; pooled descriptive analyses were presented to illustrate trends, consistent with PRISMA-ScR methodology.

RESULTS

A total of 4783 articles were identified, of which 32 met the inclusion criteria. Of the 32 studies analyzed, 24 were conducted in Europe, 5 in the United States, and 1 each in China, Korea, and New Zealand. Study designs comprised 27 retrospective observational studies, 3 randomized controlled trials, one prospective case series and one ambispective cohort study. Open reduction and internal fixation remain the standard surgical method, while alternatives such as tibiotalocalcaneal nailing and fibular intramedullary nailing are increasingly reported. Overall functional recovery was satisfactory, but outcomes varied by comorbidity burden, fracture pattern, and rehabilitation strategy. Complication rates were substantial, with wound problems, fixation failure, and infections most frequent. Mortality ranged from 10 to 27%, with higher rates in nonoperative and frail populations. Evidence on weight-bearing protocols and long-term outcomes remains inconsistent.

CONCLUSIONS

Current evidence supports surgery as the preferred option for most elderly ankle fractures, though individualized, multidisciplinary care is essential. Research gaps include standardized fixation protocols, comorbidity-adjusted pathways, and long-term functional outcomes. High-quality prospective studies are needed to refine clinical recommendations.

摘要

目的

踝关节骨折在老年人中越来越常见,由于骨质疏松、合并症和身体虚弱,带来了独特的挑战。治疗方法仍存在争议,虽然最佳方法存在争议,但手术固定通常更受青睐。本范围综述旨在梳理65岁及以上患者踝关节骨折治疗的现有证据,突出治疗策略、结果及知识空白。

方法

按照系统评价和Meta分析扩展版的首选报告项目(PRISMA-ScR)进行范围综述。我们系统检索了2010年至2024年的PubMed、Embase和Cochrane图书馆。纳入报告老年患者治疗结果的合格研究。数据进行图表记录并进行叙述性总结;呈现汇总描述性分析以说明趋势,这与PRISMA-ScR方法一致。

结果

共识别出4783篇文章,其中32篇符合纳入标准。在分析的32项研究中,24项在欧洲进行,5项在美国进行,中国、韩国和新西兰各有1项。研究设计包括27项回顾性观察研究、3项随机对照试验、1项前瞻性病例系列研究和1项双向队列研究。切开复位内固定仍然是标准的手术方法,而胫距跟骨钉固定和腓骨髓内钉固定等替代方法的报道越来越多。总体功能恢复令人满意,但结果因合并症负担、骨折类型和康复策略而异。并发症发生率较高,伤口问题、固定失败和感染最为常见。死亡率在10%至27%之间,非手术和身体虚弱人群的死亡率更高。关于负重方案和长期结果的证据仍然不一致。

结论

目前的证据支持手术作为大多数老年踝关节骨折的首选治疗方法,但个体化的多学科护理至关重要。研究空白包括标准化固定方案、合并症调整路径和长期功能结果。需要高质量的前瞻性研究来完善临床建议。

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