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直立位0.5T开放式磁共振排便造影概念验证研究:使用坐位造影评估盆底测量的评分者间和评分者内变异性。

Upright 0.5 T open MR defaecating proctography proof of concept study: the inter- and intra-rater variability of pelvic floor measures using seated proctography.

作者信息

Sobhan Rashed, Glover Paul M, Gowland Penny A, Munyal Rahul, Mougin Olivier E, Clarke Christopher G D

机构信息

Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, NG7 2RD, UK.

NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.

出版信息

MAGMA. 2025 Sep 13. doi: 10.1007/s10334-025-01296-6.

DOI:10.1007/s10334-025-01296-6
PMID:40944878
Abstract

OBJECTIVE

We tested the feasibility, data quality, and reliability of an upright magnetic resonance defaecating proctography (uMRDP) technique using an Open 0.5 T ASG MRI scanner.

MATERIALS AND METHODS

Eight healthy volunteers (2 males) performed seated defaecation on a purpose-built radio-frequency commode coil in an Open scanner. An optimised T2-weighted HASTE sequence captured dynamic changes during all three phases of the Kegel manoeuvre. Inter- and intra-rater variability was measured from the pelvic floor (PF) metrices (M-line, H-line, distances of landmarks) extracted by two radiologists.

RESULTS

All relevant PF landmarks could be identified and metrices were extracted with acceptable inter- and intra-rater variability. Intra-rater variation was marginal, with relative absolute differences ranging from 5 to 21% and 3.2-44%. Inter-rater variability was reported using correlation and Bland-Altman plots. Correlation between raters was satisfactory, with r > 0.93, and bias ranged from - 1.8 to 0.65 mm. Moreover, the limit of agreement in the Bland-Altman plot ranged from 5.8 to 20.4 mm, indicating satisfactory precision.

DISCUSSION

The proposed uMRDP technique can be used as a feasible and reliable alternative to supine MRDP, without the necessity of gadolinium injection and bowel preparation. It can capture defaecation in a regular seated posture and can provide information complementary to standard-of-care fluoroscopic proctography for clinicians.

摘要

目的

我们使用开放式0.5T ASG MRI扫描仪测试了直立式磁共振排粪造影(uMRDP)技术的可行性、数据质量和可靠性。

材料与方法

8名健康志愿者(2名男性)在开放式扫描仪中专门设计的射频便盆线圈上进行坐姿排便。优化后的T2加权HASTE序列捕捉了凯格尔运动三个阶段的动态变化。由两名放射科医生从盆底(PF)指标(M线、H线、标志点距离)测量评分者间和评分者内的变异性。

结果

所有相关的PF标志点均可识别,指标提取的评分者间和评分者内变异性均可接受。评分者内变异很小,相对绝对差异范围为5%至21%和3.2%至44%。使用相关性和布兰德-奥特曼图报告评分者间的变异性。评分者之间的相关性令人满意,r > 0.93,偏差范围为-1.8至0.65毫米。此外,布兰德-奥特曼图中的一致性界限范围为5.8至20.4毫米,表明精度令人满意。

讨论

所提出的uMRDP技术可作为仰卧位MRDP的一种可行且可靠的替代方法,无需注射钆造影剂和肠道准备。它可以捕捉常规坐姿下的排便情况,并可为临床医生提供补充标准护理荧光透视排粪造影的信息。

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[Ga]Ga-NODAGA-E[(cRGDyK)] Angiogenesis PET/MR in a Porcine Model of Chronic Myocardial Infarction.
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