McNee Anne Elizabeth, Ashby Elizabeth, Trees Amanda, Baird Emily, Campbell Donald M, Gelfer Yael
Paediatric Orthopaedic Department, Chelsea and Westminster NHS Foundation Trust, London, UK.
Imperial College, London, UK.
Bone Jt Open. 2025 Sep 15;6(9):1109-1114. doi: 10.1302/2633-1462.69.BJO-2025-0103.R1.
Clubfoot is the most common congenital foot deformity. Clubfoot management is lacking high-quality research to support clinical decision-making. It has been chosen as one of the elective priorities in research by the James Lind Alliance priority setting. We present the protocol of a consensus-based approach to identify research priorities for clinical trials in clubfoot management.
A modified Delphi technique will be used, which will involve an initial scoping survey, a two-round Delphi process, and a consensus meeting. The survey will be conducted among key stakeholders in the management of clubfoot, as well as patients and carers in the UK. The priorities identified during this process will each be assigned to core areas of consideration. The final list of research priorities will then be discussed and agreed in a consensus meeting of representative key stakeholders.
While treatment of clubfoot has become more consistent with the use of the Ponseti method, most research is retrospective from single centres, and outcomes are variable. Identifying research priorities in this group of patients through this study will shape and drive the development of multicentre prospective clinical trials deemed most important for improving clinical practice and health outcomes.
马蹄内翻足是最常见的先天性足部畸形。马蹄内翻足的治疗缺乏高质量研究来支持临床决策。它已被詹姆斯·林德联盟优先事项设定选为研究的选修重点之一。我们提出了一种基于共识的方法的方案，以确定马蹄内翻足治疗临床试验的研究重点。
将使用改良的德尔菲技术，包括初步范围调查、两轮德尔菲过程和一次共识会议。调查将在马蹄内翻足治疗的关键利益相关者以及英国的患者和护理人员中进行。在此过程中确定的重点将分别分配到核心考虑领域。然后，研究重点的最终清单将在代表性关键利益相关者的共识会议上进行讨论并达成一致。
虽然马蹄内翻足的治疗因使用庞塞蒂方法而变得更加一致，但大多数研究是来自单一中心的回顾性研究，结果各不相同。通过本研究确定这组患者的研究重点将塑造并推动多中心前瞻性临床试验的发展，这些试验被认为对改善临床实践和健康结果最为重要。
