Hirasawa Yusuke, Seiya Yuuka, Koyama Erika, Uchiyama Nahoko, Nagamura Mayu, Endo Daishi, Morita Hiroshi
Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-Ku, Tokyo, 142-8501, Japan.
National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki‑Ku, Kawasaki, Kanagawa, 210‑9501, Japan.
J Nat Med. 2025 Sep 14. doi: 10.1007/s11418-025-01943-1.
Three novel triterpenoids, yatiaroic acids A-C (1-3) with an unprecedented seco-serratane skeleton were isolated from branches of Myrica gale var. tomentosa. The relative and absolute stereochemistry of 1-3 were determined on the basis of the 2D NMR data, chemical transformation, and CD calculation.
从绒毛杨梅变种的枝条中分离出三种具有前所未有的裂环羽扇豆烷骨架的新型三萜类化合物，即亚替阿罗酸A-C（1-3）。基于二维核磁共振数据、化学转化和圆二色计算确定了1-3的相对和绝对立体化学。
